SynthesisEpidemiology and health2024
Handgrip strength thresholds associated with metabolic syndrome risk in children and adolescents: a systematic review and meta-analysis.
Synthesis in Epidemiology and health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Handgrip Strength Thresholds to Detect Cardiometabolic Risk in Youth: Cross-Sectional Study and Meta-Analysis.Journal of cachexia, sarcopenia and muscle · 2025Pooled it
- Updated Age- and Sex-Specific Reference Values and Anthropometric Correlates of Maximum Handgrip Strength in Preschool Children from the Araucanía Region, Chile.Children (Basel, Switzerland) · 2026Article
- Handgrip Strength in Korean Youth and Young Adults: Reference Values and Their Associations with Metabolic Syndrome.Journal of obesity & metabolic syndrome · 2026Article
- Trends and distributional characteristics in handgrip strength of 1,082,296 children and adolescents in China: an analysis from five representative cross-sectional surveys from 2000 to 2019.BMC public health · 2025Article
- Construct prediction models for low muscle mass with metabolic syndrome using machine learning.PloS one · 2025Article
- Disability-Related Disparities in Preventive Healthcare Access in South Korea: Insights From National Health Insurance Data.International journal of public health · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesCertain studies have reported that handgrip strength (HGS) is associated with metabolic health risks in children and adolescents, and some studies have suggested HGS thresholds for identifying poor metabolic health. Therefore, we aimed to determine the HGS thresholds associated with metabolic syndrome (MetS) in children and adolescents through a systematic review.
methodsWe searched 3 electronic databases from their inception until October 2023 to identify original papers that focused on children and adolescents and assessed their risks of MetS according to specific HGS values. Studies were selected for inclusion through a planned screening process based on specific criteria. The Quality Assessment Tool for Diagnostic Accuracy Studies version 2 (QUADAS-2) was used to evaluate quality, and a meta-analysis was performed using the diagmeta R package to suggest the optimal thresholds.
resultsFrom the search, 8 studies were selected for this systematic review. For detecting MetS risk, the optimal threshold for HGS (defined as relative HGS by adjusting for body mass) was found to be 0.422, with a sensitivity of 76.7% (95% confidence interval [CI], 64.0 to 85.8) and a specificity of 62.9% (95% CI, 56.9 to 68.5). The stratification analysis by sex resulted in optimal thresholds of 0.416 for boys and 0.376 for girls. Additionally, when the data were stratified by age, the thresholds were 0.356 for children and 0.416 for adolescents.
conclusionsOur results provide practical information for detecting high-risk groups and encouraging strength-related activities that may reduce the risk of MetS in children and adolescents.
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