ArticleAJNR. American journal of neuroradiology2024
Improved Cerebral Glymphatic Flow after Transvenous Embolization of CSF-Venous Fistula.
Article in AJNR. American journal of neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Patient-reported outcomes after surgical treatment of spontaneous intracranial hypotension: a cross-sectional study.Acta neurologica Belgica · 2026Article
- Low interstitial fluid in patients with spontaneous intracranial hypotension.Fluids and barriers of the CNS · 2026Article
- Spontaneous Intracranial Hypotension and CSF-Venous Fistulae: from Diagnostic Imaging to Interventional Management.Clinical neuroradiology · 2026Review
- The parasagittal dural space of the human brain.Brain : a journal of neurology · 2025Review
- Revisiting a Rare Anomaly Described 25 Years Ago in theAJNR. American journal of neuroradiology · 2025Article
- Optic Nerve Sheath Dilation Is a Possible Marker of CSF Dyshomeostasis in Idiopathic Intracranial Hypertension.Clinical neuroradiology · 2025Article
- Spinal CSF Leaks: The Neuroradiologist Transforming Care.AJNR. American journal of neuroradiology · 2024Article
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Authors and funding
5 authors.
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Abstract
Spontaneous intracranial hypotension is characterized by symptoms of low intracranial CSF volume due to various mechanisms of CSF leakage. One such mechanism is a CSF-venous fistula, treatable with transvenous embolization resulting in substantial radiographic and clinical improvement. However, the exact mechanisms underlying these improvements, including the potential involvement of the glymphatic system, remain unclear. To noninvasively assess glymphatic clearance in spontaneous intracranial hypotension, we used an advanced MR imaging technique called the DTI along the perivascular spaces in 3 patients with CSF-venous fistula before and after embolization. All 3 patients with spontaneous intracranial hypotension initially had low glymphatic flow, which improved postembolization. Two patients with symptomatic improvement exhibited a more substantial increase in glymphatic flow compared with a patient with minimal improvement. These findings suggest a possible link between cerebral glymphatics in spontaneous intracranial hypotension pathophysiology and symptomatic improvement, warranting larger studies to explore the role of the glymphatic system in spontaneous intracranial hypotension.
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