Evidence map›Paper›PMID 38696467›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast.

Elie Marcel Teyssonnière, Pauline Trébulle, Julia Muenzner, Victor Loegler, Daniela Ludwig, Fatma Amari, Michael Mülleder, Anne Friedrich, Jing Hou, Markus Ralser and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
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  4. Production of Recombinant Hemoglobin inFoods (Basel, Switzerland) · 2026
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  14. Domestication drives repeated evolution of sexual-asexual life cycle trade-offs in yeast.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  15. Deciphering the role ofMicrobiology spectrum · 2026
    Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Elie Marcel Teyssonnière *UMR 7156 Génétique Moléculaire, Génomique et Microbiologie, Université de Strasbourg, CNRS, Strasbourg 67000, France.
Pauline Trébulle *The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, United Kingdom.
Julia Muenzner *Department of Biochemistry, Charitéplatz 1, Charité - Universitätsmedizin Berlin, Berlin 10117, Germany.
Victor LoeglerUMR 7156 Génétique Moléculaire, Génomique et Microbiologie, Université de Strasbourg, CNRS, Strasbourg 67000, France.
Daniela LudwigDepartment of Biochemistry, Charitéplatz 1, Charité - Universitätsmedizin Berlin, Berlin 10117, Germany.
Fatma AmariDepartment of Biochemistry, Charitéplatz 1, Charité - Universitätsmedizin Berlin, Berlin 10117, Germany.
Michael MüllederCore Facility High-Throughput Mass Spectrometry, Charitéplatz 1, Charité - Universitätsmedizin Berlin, Berlin 10117, Germany.
Anne FriedrichUMR 7156 Génétique Moléculaire, Génomique et Microbiologie, Université de Strasbourg, CNRS, Strasbourg 67000, France.ORCID 0000-0003-3558-9356
Jing HouUMR 7156 Génétique Moléculaire, Génomique et Microbiologie, Université de Strasbourg, CNRS, Strasbourg 67000, France.
Markus RalserThe Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, United Kingdom.
Joseph SchachererUMR 7156 Génétique Moléculaire, Génomique et Microbiologie, Université de Strasbourg, CNRS, Strasbourg 67000, France.ORCID 0000-0002-6606-6884

Funding

Species-wide survey of the phenotypic impact of genomic structural variation in yeastR01GM147040 · NIGMS · UNIVERSITY OF WASHINGTON · PI DUNHAM, MAITREYA J · 2022 to 2025
$1.1M
NIGMS NIH HHS R01 GM147040Wellcome Trust
6 · The paper itself

Abstract

Gene expression varies between individuals and corresponds to a key step linking genotypes to phenotypes. However, our knowledge regarding the species-wide genetic control of protein abundance, including its dependency on transcript levels, is very limited. Here, we have determined quantitative proteomes of a large population of 942 diverse natural

Indexed as

Gene Expression Regulation, FungalProteomeQuantitative Trait LociSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscriptomeGene Expression ProfilingGenetic VariationGenotypePhenotypeProteomicsProteomeSaccharomyces cerevisiae Proteinsgene regulationgenetic controlpQTLquantitative proteomesyeast

Identifiers

PMID38696467
PMCPMC11087752

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.