Evidence map›Paper›PMID 38696103›Full record

ArticleCell biochemistry and biophysics2024

Synthesized Gold Nanoparticles with Moringa Oleifera leaf Extract Induce Mitotic Arrest (G2/M phase) and Apoptosis in Dalton's Lymphoma Cells.

Sandeep Kumar, Alok Shukla, Surya Pratap Singh, Rishi Kant Singh, Anand Kumar Patel, Praveen Kumar Verma, Sanjay Kumar, Naveen Kumar, Varsha Singh, Kirti Wasnik and 1 more

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Article in Cell biochemistry and biophysics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Sandeep KumarDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India.
Alok ShuklaDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India.
Surya Pratap SinghThe University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Rishi Kant SinghDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India.
Anand Kumar PatelDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India.
Praveen Kumar VermaDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India.
Sanjay KumarDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India.
Naveen KumarDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India.
Varsha SinghDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India.
Kirti WasnikSchool of Biomedical Engineering, Indian Institute of Technology (BHU), Varanasi, India.
Arbind AcharyaDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India. acharya@bhu.ac.in.
Banaras Hindu University · INUniversity of Oklahoma Health Sciences Center · US

Funding

ICMR-DHR, New Delhi P-014/0774
6 · The paper itself

Abstract

The therapeutic potential of chemically synthesized AuNPs has been demonstrated in various types of cancer. However, gold nanoparticles (AuNPs) synthesized using typical chemical methods have concerns regarding their environmental safety and adverse impact on human well-being. To overcome this issue, we used an environmentally friendly approach in which gold nanoparticles were synthesized using Moringa oleifera leaf extract (MLE). The present research was mainly focused on the biosynthesis and characterization of gold nanoparticles (AuNPs) using Moringa oleifera leaf extract (MLE-AuNPs) and explore its anticancer potential against Dalton's Lymphoma (DL) cells. Characterization of the MLE-AuNPs was conducted using UV-Vis Spectroscopy to confirm the reduction process, FTIR analysis to ascertain the presence of functional groups, and XRD analysis to confirm the crystallinity. SEM and TEM images were used to examine size and morphology. After characterization, MLE-AuNPs were evaluated for their cytotoxic effects on Dalton's lymphoma cells, and the results showed an IC

Indexed as

ApoptosisGoldMetal NanoparticlesMoringa oleiferaPlant ExtractsPlant LeavesAnimalsCell Line, TumorG2 Phase Cell Cycle CheckpointsHumansLymphomaMiceMitosisGoldPlant ExtractsApoptosisCell cycleDalton’s lymphomaGold NanoparticlesMoringa oleifera

Identifiers

PMID38696103
OpenAlexW4396588529

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.