Evidence map›Paper›PMID 38696087›Full record

ArticleCancer2024

Racialized inequities in live birth after cancer: A population-based study of 63,000 female adolescents and young adults with cancer.

Andrea C Betts, Michael E Roth, Karen Albritton, Sandi L Pruitt, Philip J Lupo, Jennifer S Wang, L Aubree Shay, Marlyn A Allicock, Caitlin C Murphy

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Andrea C BettsUniversity of Texas Health Science Center at Houston, School of Public Health, Dallas, Texas, USA.ORCID https://orcid.org/0000-0003-0884-6513
Michael E RothDivision of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Karen AlbrittonCook Children's Health Care System, Fort Worth, Texas, USA.
Sandi L PruittPeter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID https://orcid.org/0000-0002-1007-9176
Philip J LupoDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.ORCID https://orcid.org/0000-0003-0978-5863
Jennifer S WangUniversity of Texas Health Science Center at Houston, School of Public Health, Dallas, Texas, USA.
L Aubree ShayUniversity of Texas Health Science Center at Houston, School of Public Health, Dallas, Texas, USA.
Marlyn A AllicockUniversity of Texas Health Science Center at Houston, School of Public Health, Dallas, Texas, USA.
Caitlin C MurphyUniversity of Texas Health Science Center at Houston, School of Public Health, Dallas, Texas, USA.ORCID https://orcid.org/0000-0001-9365-0691
University of Texas Health Science Center at Dallas · USBaylor College of Medicine · USCook Children's Health Care System · USTexas Oncology · USThe University of Texas MD Anderson Cancer Center · US

Funding

NRSA Training CoreTL1TR003169 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CHANDRA, JOYA, FROST, JEFFREY A. · 2019 to 2023
$3.7M
Qualification and Deployment of Imaging Biomarkers of Cancer Treatment ResponseU01CA190214 · NCI · STANFORD UNIVERSITY · PI RUBIN, DANIEL L · 2015 to 2020
$3.1M
Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston TL1TR003169NCATS NIH HHS TL1 TR003169NCI NIH HHS U01 CA190214US Department of Defense CA181215US Department of Defense CA190214
6 · The paper itself

Abstract

introductionFertility after cancer is a top concern for adolescents and young adults with cancer (AYAs) (15-39 years old at diagnosis). The authors characterized live births after cancer by race and ethnicity ("race/ethnicity") in a population-based sample of female AYAs.

methodsThis study used Texas Cancer Registry data linked to birth certificates (1995-2016) to estimate cumulative incidence of live birth, based on first live birth after cancer, and compared differences by race/ethnicity. Proportional subdistribution hazards models were used to estimate associations between race/ethnicity and live birth, adjusted for diagnosis age, cancer type, stage, year, and prior live birth, overall and for each cancer type.

resultsAmong 65,804 AYAs, 10-year cumulative incidence of live birth was lower among non-Hispanic Black AYAs than other racial/ethnic groups: 10.2% (95% confidence interval [CI], 9.4-10.9) compared to 15.9% (95% CI, 14.1-17.9) among Asian or Pacific Islander, 14.7% (95% CI, 14.2-15.3) among Hispanic, and 15.2% (95% CI, 14.8-15.6) among non-Hispanic White AYAs (p < .01). In the adjusted overall model, Black AYAs were less likely to have a live birth after cancer than all other groups. In adjusted models for each cancer type, live birth was significantly less likely for Black AYAs with gynecologic cancers or lymphomas (compared to White AYAs) or thyroid cancers (compared to Hispanic AYAs).

conclusionBlack AYAs are less likely than AYAs of other races/ethnicities to have a live birth after cancer, in contrast to patterns of live birth in the general population. Research and action to promote childbearing equity after cancer are imperative.

Indexed as

Cancer SurvivorsLive BirthNeoplasmsAdolescentAdultBlack or African AmericanFemaleHispanic or LatinoHumansIncidenceRegistriesTexasWhiteYoung Adultadolescent and young adult cancerbirth outcomescancer survivorshipfertilityhealth equity

Identifiers

PMID38696087
PMCPMC11364139
OpenAlexW4396578000

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.