Evidence map›Paper›PMID 38696063›Full record

ArticleEJNMMI radiopharmacy and chemistry2024

GMP production of [

Mélodie Ferrat, Mohammad M Moein, Carmen Cananau, Tetyana Tegnebratt, Paul Saliba, Fredrik Norman, Carsten Steiger, Klas Bratteby, Erik Samén, Kenneth Dahl and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Mélodie FerratDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden. melodie.ferrat@ki.se.ORCID http://orcid.org/0000-0001-7004-3565
Mohammad M MoeinDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Carmen CananauDepartment of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Tetyana TegnebrattDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Paul SalibaDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Fredrik NormanDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Carsten SteigerDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Klas BrattebyDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Erik SaménDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Kenneth DahlDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Thuy A TranDepartment of Radiopharmacy, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Karolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParkinson's disease is a neurodegenerative disorder that is characterized by a degeneration of the dopaminergic system. Dopamine transporter (DAT) positron emission tomography (PET) imaging has emerged as a powerful and non-invasive method to quantify dopaminergic function in the living brain. The PET radioligand, [

resultsThus, a fully automated and GMP-compliant production procedure has been developed using a commercially available radiosynthesis module GE TRACERLab FX2 N. [

conclusionThe protocol reliably provides a sterile and pyrogen-free GMP-compliant product.

Indexed as

[18F]FE-PE2IAutomationDopamine transporter (DAT)Fluorine-18GE TRACERLab FX2 NGMPPETRadiochemistry

Identifiers

PMID38696063
PMCPMC11065837
OpenAlexW4396581414

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.