Evidence map›Paper›PMID 38695924›Full record

ArticleIntensive care medicine2024

Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study.

Shannon M Fernando, Danial Qureshi, Robert Talarico, Simone N Vigod, Daniel I McIsaac, Lee H Sterling, Sean van Diepen, Susanna Price, Pietro Di Santo, Kwadwo Kyeremanteng and 12 more

Abstract read
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 11 institutions in 5 countries.

Shannon M FernandoDivision of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, Canada. sfernando@qmed.ca.ORCID 0000-0003-4549-4289
Danial QureshiNuffield Department of Population Health, University of Oxford, Oxford, UK.
Robert TalaricoClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Simone N VigodICES, Toronto, ON, Canada.
Daniel I McIsaacClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Lee H SterlingDivision of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Sean van DiepenDepartment of Critical Care Medicine, University of Alberta, Edmonton, AB, Canada.
Susanna PriceRoyal, Brompton & Harefield Hospitals, London, UK.
Pietro Di SantoDivision of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
Kwadwo KyeremantengDivision of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
Eddy FanInstitute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Dale M NeedhamDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Daniel BrodieDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Oscar Joseph BienvenuDepartment of Psychiatry and Behavioural Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Alain CombesInstitute of Cardiometabolism and Nutrition, Sorbonne University, Paris, France.
Arthur S SlutskyInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Damon C ScalesICES, Toronto, ON, Canada.
Margaret S HerridgeInstitute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Holger ThieleDepartment of Internal Medicine/Cardiology, Heart Center Leipzig at the University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.
Benjamin HibbertDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Peter Tanuseputro *Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Rebecca Mathew *Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
University of Ottawa · CAJohns Hopkins University · USUniversity of Toronto · CASt. Michael's Hospital · CAHarefield Hospital · GBLeipzig Heart Institute · DEMayo Clinic in Arizona · USOttawa Hospital · CASorbonne Université · FRUniversity of Alberta · CAUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCardiogenic shock secondary to acute myocardial infarction (AMI-CS) is associated with substantial short- and long-term morbidity and mortality. However, there are limited data on mental health sequelae that survivors experience following discharge.

methodsWe conducted a retrospective, population-based cohort study in Ontario, Canada of critically ill adult (≥ 18 years) survivors of AMI-CS, admitted to hospital between April 1, 2009 and March 31, 2019. We compared these patients to AMI survivors without shock. We captured outcome data using linked health administrative databases. The primary outcome was a new mental health diagnosis (a composite of mood, anxiety, or related disorders; schizophrenia/psychotic disorders; and other mental health disorders) following hospital discharge. We secondarily evaluated incidence of deliberate self-harm and death by suicide. We compared patients using overlap propensity score-weighted, cause-specific proportional hazard models.

resultsWe included 7812 consecutive survivors of AMI-CS, from 135 centers. Mean age was 68.4 (standard deviation (SD) 12.2) years, and 70.3% were male. Median follow-up time was 767 days (interquartile range (IQR) 225-1682). Incidence of new mental health diagnosis among AMI-CS survivors was 109.6 per 1,000 person-years (95% confidence interval (CI) 105.4-113.9), compared with 103.8 per 1000 person-years (95% CI 102.5-105.2) among AMI survivors without shock. After propensity score adjustment, there was no difference in the risk of new mental health diagnoses following discharge [hazard ratio (HR) 0.99 (95% CI 0.94-1.03)]. Factors associated with new mental health diagnoses following AMI-CS included female sex, pre-existing mental health diagnoses, and discharge to a long-term hospital or rehabilitation institute.

conclusionSurvivors of AMI-CS experience substantial mental health morbidity following discharge. Risk of new mental health diagnoses was comparable between survivors of AMI with and without shock. Future research on interventions to mitigate psychiatric sequelae after AMI-CS is warranted.

Indexed as

Myocardial InfarctionShock, CardiogenicSurvivorsAgedAged, 80 and overCohort StudiesFemaleHumansIncidenceMaleMental DisordersMental HealthMiddle AgedOntarioRetrospective StudiesCardiogenic shockChronic critical illnessIntensive careMental healthMyocardial infarctionPost-intensive care syndromeSelf-harmSuicide

Identifiers

PMID38695924
OpenAlexW4396577913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.