ArticleThe journal of spinal cord medicine2025
Nerve transfer for upper extremity reanimation in people with spinal cord injury: A 2-year follow-up case series.
Article in The journal of spinal cord medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Nerve and Tendon Transfers After Cervical Spinal Cord Injury: A Systematic Review of Strength Outcomes in 959 Patients.Journal of hand surgery global online · 2027Article
- Neurophysiological Recovery Following Nerve Transfer Surgery to Restore Upper Limb Function after Cervical Spinal Cord Injury.Annals of neurology · 2026Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe the 2-year functional outcomes of nerve transfer (NT) for upper extremity reanimation. STUDY
designA prospective case series.
settingA highly specialized rehabilitation hospital for spinal cord injury (SCI) in Italy.
interventionUpper limb nerve transfer (32 NTs, 15 upper limbs).
participantsTwelve male individuals with traumatic SCI (AIS A or B, neurological level from C4 to C7) were enrolled; 24-month follow-up data were available for 11. OUTCOME MEASURES: We evaluated the strength recovery of recipient muscles through the Medical Research Council (MRC) Scale for Muscle Strength. Upper limb function and independence were assessed with the Graded Redefined Assessment of Strength Sensibility and Prehension (GRASSP) test version 1 and the Spinal Cord Independent Measure III (SCIM III). Patient satisfaction was also evaluated.
resultsAfter 24 months, median MRC scores (range) were: triceps 2 (1-2); extensor digitorum communis 3 (1-4); extensor pollicis longus 2.5 (1-4); flexor digitorum profundus 2 (0-4); flexor pollicis longus 2 (0-4). No complication occurred. GRASSP prehension ability and prehension performance total scores significantly improved at 24 months from 1 (0-4) to 2 (0-7) and from 1 (0-8) to 5 (0--22), respectively. The SCIM III self-care sub-scale score improved at 24-month follow-up (
conclusionsNT represents a functional surgery option with few complications for the resuscitation of upper limbs in persons with tetraplegia.
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