Evidence map›Paper›PMID 38695538›Full record

ArticleJournal of virology2024

KSHV genome harbors both constitutive and lytically induced enhancers.

Nilabja Roy Chowdhury, Vyacheslav Gurevich, Meir Shamay

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nilabja Roy ChowdhuryDaniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.ORCID 0000-0003-1262-4972
Vyacheslav GurevichDaniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Meir ShamayDaniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.ORCID 0000-0003-0223-2852
Bar-Ilan University · IL

Funding

Israel Cancer Research Fund (ICRF) 23-101-PGIsrael Science Foundation (ISF) 1365/21
6 · The paper itself

Abstract

Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-herpesvirus family and is a well-known human oncogenic virus. In infected cells, the viral genome of 165 kbp is circular DNA wrapped in chromatin. The tight control of gene expression is critical for latency, the transition into the lytic phase, and the development of viral-associated malignancies. Distal

Indexed as

Enhancer Elements, GeneticGene Expression Regulation, ViralGenome, ViralHerpesvirus 8, HumanPromoter Regions, GeneticVirus ActivationVirus LatencyAntigens, ViralChromatinHEK293 CellsHumansImmediate-Early ProteinsNuclear ProteinsTerminal Repeat SequencesTrans-ActivatorsAntigens, ViralChromatinImmediate-Early Proteinslatency-associated nuclear antigenNuclear ProteinsRta protein, Human herpesvirus 8Trans-ActivatorsenhancerFAIREHHV-8KSHVLANARTAsilencerSTARR-seq

Identifiers

PMID38695538
PMCPMC11237633
OpenAlexW4396581317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.