Evidence map›Paper›PMID 38695059›Full record

Trial reportThe journals of gerontology. Series A, Biological sciences and medical sciences2024

Hearing Impairment and Physical Activity and Physical Functioning in Older Adults: Baseline Results From the ACHIEVE Trial.

Yurun Cai, Pablo Martinez-Amezcua, Joshua F Betz, Talan Zhang, Alison R Huang, Amal A Wanigatunga, Nancy W Glynn, Sheila Burgard, Theresa H Chisolm, Josef Coresh and 15 more

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The journals of gerontology. Series A, Biological sciences and medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 7 institutions in 2 countries.

Yurun CaiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0001-8264-8158
Pablo Martinez-AmezcuaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-3076-0946
Joshua F BetzDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-4488-9799
Talan ZhangCenter on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA.
Alison R HuangDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Amal A WanigatungaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-5763-5184
Nancy W GlynnDepartment of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2265-0162
Sheila BurgardDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Theresa H ChisolmDepartment of Communication Sciences and Disorders, College of Behavioral and Community Sciences, University of South Florida, Tampa, Florida, USA.
Josef CoreshDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
David CouperDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-4313-9235
Jennifer A DealDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-6985-048X
Theresa GmelinDepartment of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.
Adele M GomanDepartments of School of Health and Social Care, Edinburgh Napier University, Edinburgh, UK.
Lisa Gravens-MuellerDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kathleen M HaydenDepartment of Social Sciences and Health Policy, School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.ORCID 0000-0002-7745-3513
Christine M MitchellDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Thomas MosleyDivision of Geriatrics, The Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, Mississippi, USA.
James S PankowDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
James R PikeDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-6858-620X
Nicholas S ReedDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-0410-6067
Victoria A SanchezDepartment of Otolaryngology - Head and Neck Surgery, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Frank R LinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Jennifer A SchrackDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0001-9244-9267
ACHIEVE Collaborative Research Group
Johns Hopkins University · USUniversity of North Carolina at Chapel Hill · USUniversity of Pittsburgh · USUniversity of South Florida · USUniversity of Minnesota · USUniversity of Mississippi Medical Center · USWake Forest University · US

Funding

ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028U01HL096812 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, THOMAS H MOSLEY · 2010 to 2026
$65.7M
Aging, Cognition, and Hearing Evaluation in Elders (ACHIEVE) Randomized TrialR01AG055426 · NIA · JOHNS HOPKINS UNIVERSITY · PI CORESH, JOSEF, LIN, FRANK R · 2017 to 2021
$16.6M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2 of 5U01HL096917 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI MOSLEY, THOMAS H · 2010 to 2018
$11.9M
ARIC Neurocognitive Study (ARIC-NCS) Renewal UNC 4 of 5U01HL096899 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID J · 2010 to 2018
$7.5M
ARIC Neurocognitive Study (ARIC-NCS)U01HL096902 · NHLBI · UNIVERSITY OF MINNESOTA · PI LUTSEY, PAMELA L. · 2010 to 2018
$7.4M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 4 of 5U01HL096814 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUGHES, TIMOTHY M., WAGENKNECHT, LYNNE E · 2010 to 2018
$6.5M
TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000181 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 1989 to 2025
$6.2M
The ARIC and Neurocognitive Longitudinal StudyR01HL070825 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI MOSLEY, THOMAS H · 2002 to 2004
$5.1M
Hearing loss, brain aging, and speech-in-noise performance in the ACHIEVE studyR01AG060502 · NIA · JOHNS HOPKINS UNIVERSITY · PI LIN, FRANK R · 2018 to 2022
$3.2M
Planning a trial of hearing rehabilitative treatment to reduce cognitive declineR34AG046548 · NIA · JOHNS HOPKINS UNIVERSITY · PI CORESH, JOSEF, LIN, FRANK R · 2014 to 2015
$626k
Eleanor Schwartz Charitable FoundationNHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002CNHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003CNHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004CNHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005CNHLBI NIH HHS HHSN268201700005INHLBI NIH HHS R01 HL070825NHLBI NIH HHS U01 HL096812NHLBI NIH HHS U01 HL096814NHLBI NIH HHS U01 HL096899NHLBI NIH HHS U01 HL096902NHLBI NIH HHS U01 HL096917NIA NIH HHS R01 AG055426NIA NIH HHS R01AG055426NIA NIH HHS R01 AG060502NIA NIH HHS R34 AG046548NIA NIH HHS T32 AG000181
6 · The paper itself

Abstract

backgroundHearing loss is associated with restricted physical activity (PA) and impaired physical functioning, yet the relationship between severity of hearing impairment (HI) and novel PA measures in older adults with untreated HI is not well understood.

methodsAnalyses included 845 participants aged ≥70 years (mean = 76.6 years) with a better-hearing ear pure-tone average (PTA) ≥30 and <70 dB in the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) study who wore an ActiGraph accelerometer for 7 days. Physical functioning measures included grip strength and the Short Physical Performance Battery (SPPB). Linear regression models estimated the association by HI level (moderate or greater [PTA ≥ 40 dB] vs mild [PTA < 40 dB]) and continuous hearing with total daily activity counts, active minutes/day, activity fragmentation, grip strength, and gait speed. Logistic regression models estimated odds ratios (ORs) and 95% confidence intervals (CIs) of poor performance on the SPPB (≤6) and its subtests (≤2). Mixed-effects models estimated differences by HI level in activity by time of day.

resultsParticipants with moderate or greater HI had poorer physical functioning, particularly balance (OR = 2.17, 95% CI = 1.29-3.67), versus those with mild impairment. There was no association of HI level with activity quantities or fragmentation. For diurnal patterns of activity, participants with moderate or greater HI had fewer activity counts in the afternoon (12:00 pm -05:59 pm).

conclusionsOlder adults with worse hearing had shifted diurnal patterns and poorer balance performance. Exercise programs should be tailored to older adults with different levels of HI to maintain PA and physical functioning, particularly balance control.

Indexed as

ExerciseHearing LossAccelerometryAgedAged, 80 and overAudiometry, Pure-ToneFemaleGeriatric AssessmentHand StrengthHumansMalePhysical Functional PerformanceAccelerometryActivity fragmentationBalance performanceDiurnal patternsHearing loss

Identifiers

PMID38695059
PMCPMC11170292
OpenAlexW4396633595

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.