ArticleJournal of pharmacy & bioallied sciences
D-optimal Design Optimization of Solvent Mixture for Flavonoid Extraction from
Article in Journal of pharmacy & bioallied sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Response Surface D-Optimal Design for Optimizing Fortimicins Production by Micromonospora olivasterospora and New Synergistic Fortimicin-A-Antibiotic Combinations.Current microbiology · 2025Article
- Optimization of ultrasonic-assisted extraction of total flavonoids fromFrontiers in microbiology · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
Aims: This study aimed to optimize the extraction of flavonoids and antioxidants from Method: The total flavonoid content (TFC) and antioxidant activity were evaluated using the colorimetric method and ferric-reducing antioxidant power (FRAP), respectively. Maceration extracts from fresh leaves were used for the analysis. The study used the Design Expert 13.0 program to optimize the solvents (water, acetone, and methanol) and their combined ratio. Result: The results showed that 100% acetone was the best solvent for both responses, with a desirability value of 0.884, TFC of 0.434 mg QE/g fresh weight (FW) and FRAP of 713.53 μmol TE/g FW. Screening of the most potent Conclusion: This study demonstrates an easy and useful way to obtain flavonoids and antioxidants from
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