Evidence map›Paper›PMID 38694886›Full record

ArticleThe mental health clinician2024

Comparison of long-acting injectable antipsychotics with oral antipsychotics and hospital readmission rates in pediatric patients.

Danial Chowdhury, Daniel Greer, Mei T Liu, Caitlin McCarthy, Megan Maroney

Open access · goldAbstract read
In one paragraph

Article in The mental health clinician, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Danial ChowdhuryClinical Assistant Professor, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, New Jersey.ORCID https://orcid.org/0000-0002-2140-3453
Daniel GreerClinical Assistant Professor, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, New Jersey.ORCID https://orcid.org/0000-0001-9997-3715
Mei T LiuClinical Assistant Professor, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, New Jersey; Clinical Psychiatric Pharmacist, Penn Medicine Princeton House Behavioral Health, Princeton, New Jersey.ORCID https://orcid.org/0000-0001-8527-9319
Caitlin McCarthyClinical Assistant Professor, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, New Jersey; Director of Pharmacy Services, Henry J. Austin Health Center, Trenton, New Jersey.ORCID https://orcid.org/0000-0002-8034-051X
Megan MaroneyClinical Associate Professor, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, New Jersey; Clinical Psychiatric Pharmacist, RWJBarnabas Monmouth Medical Center, Long Branch, New Jersey.ORCID https://orcid.org/0000-0002-2718-6787
Rutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Studies indicate that long-acting injectable antipsychotics (LAIAs) reduce the risk of relapse and hospitalization compared with oral antipsychotics (APs) in adults. Oral formulations of APs are well-studied in the pediatric population, but little is known regarding the off-label use of LAIAs in this population. Methods: This retrospective chart review evaluated readmission rates for pediatric patients admitted to a psychiatric ward in a large academic hospital between January 1, 2015, and December 1, 2022, requiring AP therapy. The experimental group included patients initiated on LAIA therapy, and the control group included patients initiated on a new oral AP. Patients were matched by several clinical factors. Results: Each group consisted of 38 patients. For the primary outcome, hospital readmission rates at 3 months, the LAIA group had a 13.2% readmission rate compared with 26.3% in the comparator group ( Discussion: In a pediatric population, the administration of an LAIA when compared with the oral equivalent resulted in numerically fewer hospital readmissions, decreased length of stay, and fewer adverse effects, but these effects were not statistically significant except for cumulative readmissions at 1 year.

Indexed as

antipsychoticsbipolar disorderinjectable therapyschizophrenia

Identifiers

PMID38694886
PMCPMC11058320
OpenAlexW4393386400

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.