Evidence map›Paper›PMID 38694657›Full record

ReviewCureus2024

Evaluating the Efficacy of Antioxidant Therapy in Enhancing the Quality of Life of Chronic Pancreatitis Patients: A Systematic Review.

Hamza Al Balushi, Junaid Ahmed, Laksh Kumar Ahuja, Fnu Barkha, Mohamed Ishraq Shafeeq, Amna B Baluch, Yahya Altinkaynak, Shenouda Abdallah, Hamza Islam, Rabia Islam and 3 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 6 countries.

Hamza Al BalushiInternal Medicine, First Bethune Hospital, Muscat, OMN.
Junaid AhmedInternal Medicine, Chandka Medical College Hospital, Larkana, PAK.
Laksh Kumar AhujaInternal Medicine, Chandka Medical College, Larkana, PAK.
Fnu BarkhaPathology, Chandka Medical College, Larkana, PAK.
Mohamed Ishraq ShafeeqMedicine and Surgery, Vitebsk State Medical University, Vitebsk, BLR.
Amna B BaluchInternal Medicine, Universidad Autonoma de Guadalajara, Guadalajara, MEX.
Yahya AltinkaynakMedical Biochemistry, Ardahan University, Ardahan, TUR.
Shenouda AbdallahSurgery, Jaber Al-Ahmad Hospital, Kuwait City, KWT.
Hamza IslamResearch, Punjab Medical College, Faisalabad, PAK.
Rabia IslamResearch, Faisalabad Medical University, Faisalabad, PAK.
Abdur RehmanMedicine and Surgery, Mayo Hospital, Lahore, PAK.
Abdullah ShehryarInternal Medicine, Allama Iqbal Medical College, Lahore, PAK.
Ali RazaInternal Medicine, Nishtar Medical University, Multan, PAK.
Chandka Medical College · PKPunjab Medical College · PKAllama Iqbal Medical College · PKArdahan University · TRFirst Bethune Hospital of Jilin University · CNJahra Hospital · KWMayo Hospital · PKNishtar Medical College and Hospital · PKUniversidad Autónoma de Guadalajara · MXVitebsk State Medical University · BY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pancreatitis (CP), an inflammatory disease characterized by irreversible pancreatic changes and progressive fibrosis, significantly impairs patients' quality of life. This systematic review aims to assess the efficacy of antioxidant therapy in enhancing the quality of life of CP patients. Focusing on the role of oxidative stress in CP pathogenesis, we explored several databases for studies evaluating the impact of antioxidant supplementation. The review included randomized controlled trials and cohort studies reporting pain frequency, intensity, and overall quality of life measures. Findings from these studies present a mixed view of the efficacy of antioxidants in CP, with some suggesting benefits in symptom management, while others show inconsistency in improving patient outcomes. The review concludes that while antioxidant therapy holds potential, especially in symptom alleviation, there is a need for more rigorous, larger-scale studies to confirm its effectiveness in CP management and to establish standardized treatment protocols. The incorporation of antioxidants into CP treatment plans should be approached with personalized care, considering the varied responses observed in different patient populations.

Indexed as

antioxidant therapychronic pancreatitisefficacyquality of lifesystematic review

Identifiers

PMID38694657
PMCPMC11062490
OpenAlexW4393384877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.