Evidence map›Paper›PMID 38694489›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2024

Tacrolimus's Time Below Therapeutic Range Is Associated With Acute Pancreatic Graft Rejection and the Development of

Diana Rodríguez-Espinosa, José Jesús Broseta, Enrique Montagud-Marrahí, Carolt Arana, Joana Ferrer, Miriam Cuatrecasas, Ángeles Garcia-Criado, Antonio J Amor, Fritz Diekmann, Pedro Ventura-Aguiar

Open access · goldAbstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Calcineurin inhibition may prevent Alzheimer disease in people with Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Diana Rodríguez-EspinosaDepartment of Nephrology and Renal Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain.
José Jesús BrosetaDepartment of Nephrology and Renal Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain.
Enrique Montagud-MarrahíDepartment of Nephrology and Renal Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain.
Carolt AranaDepartment of Nephrology and Renal Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain.
Joana FerrerDepartment of Hepatobiliopancreatic Surgery and Liver Transplant, Hospital Clínic, Barcelona, Spain.
Miriam CuatrecasasDepartment of Pathology, Hospital Clínic Barcelona, Barcelona, Spain.
Ángeles Garcia-CriadoDepartment of Radiology, Hospital Clínic Barcelona, Barcelona, Spain.
Antonio J AmorDiabetes Unit, Department of Endocrinology and Nutrition, Hospital Clínic Barcelona, Barcelona, Spain.
Fritz DiekmannDepartment of Nephrology and Renal Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain.
Pedro Ventura-AguiarDepartment of Nephrology and Renal Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain.
Hospital Clínic de Barcelona · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tacrolimus is pivotal in pancreas transplants but poses challenges in maintaining optimal levels due to recipient differences. This study aimed to explore the utility of time spent below the therapeutic range and intrapatient variability in predicting rejection and

Indexed as

Graft RejectionImmunosuppressive AgentsPancreas TransplantationTacrolimusAdultBiopsyFemaleGraft SurvivalHumansIsoantibodiesMaleMiddle AgedRetrospective StudiesTime FactorsTissue DonorsImmunosuppressive AgentsIsoantibodiesTacrolimusFKpancreas transplantationtacrolimustime in therapeutic rangeTTR

Identifiers

PMID38694489
PMCPMC11062183
OpenAlexW4394879587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.