Evidence map›Paper›PMID 38694201›Full record

ArticleResearch (Washington, D.C.)2024

Single-Round Circular Aptamer Discovery Using Bioinspired Magnetosome-Like Magnetic Chain Cross-Linked Graphene Oxide.

Lili Yao, Junmei Feng, Yuefei Zhou, Shengjie Gao, Shuai Liu, Hao Qu, Yu Mao, Lei Zheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Research (Washington, D.C.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lili YaoSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID https://orcid.org/0009-0008-9562-7549
Junmei FengSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID https://orcid.org/0009-0005-8633-5227
Yuefei ZhouSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID https://orcid.org/0009-0009-2141-7028
Shengjie GaoSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID https://orcid.org/0009-0006-1605-614X
Shuai LiuSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID https://orcid.org/0000-0001-8319-6376
Hao QuSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID https://orcid.org/0000-0002-5834-8080
Yu MaoSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID https://orcid.org/0000-0002-4656-2864
Lei ZhengSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID https://orcid.org/0000-0002-4656-2864

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular aptamers are promising candidates for analytical and therapeutic applications due to their enhanced biological and structural stability. However, the process of circular aptamer selection remains a great challenge, as it requires multiple rounds of binding-separation-amplification that involves issues with nonspecific binding and amplification bias. Here, we develop a highly practical solution for reliable selection of circular aptamers in a single round based on magnetosome-like magnetic chain cross-linked graphene oxide (separation efficiency ≈ 10

Identifiers

PMID38694201
PMCPMC11062507

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.