Evidence map›Paper›PMID 38693874›Full record

ArticleBiomacromolecules2024

Positively Charged Biodegradable Polymersomes with Structure Inherent Fluorescence as Artificial Organelles.

Roy A J F Oerlemans, Shoupeng Cao, Jianhong Wang, Yudong Li, Yingtong Luo, Jingxin Shao, Loai K E A Abdelmohsen, Jan C M van Hest

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Peptide-Induced Division of Polymersomes for Biomimetic Compartmentalization.Angewandte Chemie (International ed. in English) · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Roy A J F OerlemansBio-Organic Chemistry, Department of Biomedical Engineering and Chemical Engineering & Chemistry, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
Shoupeng CaoBio-Organic Chemistry, Department of Biomedical Engineering and Chemical Engineering & Chemistry, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.ORCID 0000-0002-5856-2407
Jianhong WangBio-Organic Chemistry, Department of Biomedical Engineering and Chemical Engineering & Chemistry, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
Yudong LiBio-Organic Chemistry, Department of Biomedical Engineering and Chemical Engineering & Chemistry, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
Yingtong LuoBio-Organic Chemistry, Department of Biomedical Engineering and Chemical Engineering & Chemistry, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.ORCID 0009-0000-2950-5625
Jingxin ShaoBio-Organic Chemistry, Department of Biomedical Engineering and Chemical Engineering & Chemistry, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.ORCID 0009-0007-8888-9172
Loai K E A AbdelmohsenBio-Organic Chemistry, Department of Biomedical Engineering and Chemical Engineering & Chemistry, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.ORCID 0000-0002-0094-1893
Jan C M van HestBio-Organic Chemistry, Department of Biomedical Engineering and Chemical Engineering & Chemistry, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.ORCID 0000-0001-7973-2404

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymersomes, nanosized polymeric vesicles, have attracted significant interest in the areas of artificial cells and nanomedicine. Given their size, their visualization via confocal microscopy techniques is often achieved through the physical incorporation of fluorescent dyes, which however present challenges due to potential leaching. A promising alternative is the incorporation of molecules with aggregation-induced emission (AIE) behavior that are capable of fluorescing exclusively in their assembled state. Here, we report on the use of AIE polymersomes as artificial organelles, which are capable of undertaking enzymatic reactions in vitro. The ability of our polymersome-based artificial organelles to provide additional functionality to living cells was evaluated by encapsulating catalytic enzymes such as a combination of glucose oxidase/horseradish peroxidase (GO

Indexed as

beta-GalactosidaseGlucose OxidaseHorseradish PeroxidaseFluorescenceFluorescent DyesHeLa CellsHumansMitochondriaOrganellesPolymersbeta-GalactosidaseFluorescent DyesGlucose OxidaseHorseradish PeroxidasePolymers

Identifiers

PMID38693874
PMCPMC11094732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.