Evidence map›Paper›PMID 38693726›Full record

ArticleCancer science2024

Impacts of tumor microenvironment during neoadjuvant chemotherapy in patients with esophageal squamous cell carcinoma.

Kotaro Sugawara, Takashi Fukuda, Chiaki Murakami, Daiji Oka, Takako Yoshii, Gulanbar Amori, Kumiko Ishibashi, Yasuhito Kobayashi, Hiroki Hara, Hiroaki Kanda and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancer science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Kotaro SugawaraDepartment of Gastroenterological Surgery, Saitama Cancer Center, Saitama, Japan.ORCID https://orcid.org/0000-0002-3272-1748
Takashi FukudaDepartment of Gastroenterological Surgery, Saitama Cancer Center, Saitama, Japan.
Chiaki MurakamiDepartment of Pathology, Saitama Cancer Center, Saitama, Japan.
Daiji OkaDepartment of Gastroenterological Surgery, Saitama Cancer Center, Saitama, Japan.
Takako YoshiiDepartment of Gastroenterology, Saitama Cancer Center, Saitama, Japan.
Gulanbar AmoriDepartment of Pathology, Saitama Cancer Center, Saitama, Japan.
Kumiko IshibashiDepartment of Pathology, Saitama Cancer Center, Saitama, Japan.
Yasuhito KobayashiDepartment of Pathology, Saitama Cancer Center, Saitama, Japan.
Hiroki HaraDepartment of Gastroenterology, Saitama Cancer Center, Saitama, Japan.
Hiroaki KandaDepartment of Pathology, Saitama Cancer Center, Saitama, Japan.
Noriko MotoiDepartment of Pathology, Saitama Cancer Center, Saitama, Japan.ORCID https://orcid.org/0000-0001-7098-3311
Saitama Cancer Center · JP

Funding

Japan Agency for Medical Research and Development 22hk0102080Japan Society for the Promotion of Science 21K06900
6 · The paper itself

Abstract

With the advent of immune checkpoint inhibitors (ICIs), a better understanding of tumor microenvironment (TME) is becoming crucial in managing esophageal squamous cell carcinoma (ESCC) patients. We investigated the survival impact of TME status and changes in patients with ESCC who underwent neoadjuvant chemotherapy (NAC) followed by surgery (n = 264). We examined immunohistochemical status (CD4

Indexed as

B7-H1 AntigenEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaNeoadjuvant TherapyTumor MicroenvironmentAdultAgedChemotherapy, AdjuvantFemaleHumansLymphocytes, Tumor-InfiltratingMaleMiddle AgedPrognosisB7-H1 AntigenCD274 protein, humanesophageal squamous cell carcinomaimmune checkpoint inhibitorneoadjuvant chemotherapysurgerytumor microenvironment

Identifiers

PMID38693726
PMCPMC11309932
OpenAlexW4396596476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.