Evidence map›Paper›PMID 38693679›Full record

SynthesisMovement disorders clinical practice2024

I

Sonia Quintas, Reyes Sanles-Falagan, M Álvaro Berbís

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Movement disorders clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Clinical and Imaging Characteristics of Parkinson's Disease with Negative Alpha-Synuclein Seed Amplification Assay.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Relevance ofScientific reports · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sonia QuintasDepartment of Neurology, La Princesa University Hospital, Madrid, Spain.ORCID 0000-0003-0622-8228
Reyes Sanles-FalaganDepartment of R&D, HT Médica, Madrid, Spain.ORCID 0000-0002-7072-8086
M Álvaro BerbísDepartment of Radiology, HT Médica, San Juan de Dios Hospital, Córdoba, Spain.ORCID 0000-0002-0331-7762
Hospital San Juan de Dios · CLHospital Universitario de La Princesa · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the diagnosis of Parkinson's disease (PD) is fundamentally clinical, the usefulness of ioflupane (

objectivesWe aimed to summarize the current literature regarding DaTSCAN findings in patients with rare neurodegenerative parkinsonisms.

methodsThe PubMed database was systematically screened for studies in English or Spanish up to October 15, 2023, using search terms "DaTSCAN", "ioflupane", "DaT-SPECT", "123I-FP-CIT SPECT", "dopamine transporter imaging", and "[123I] FP-CIT SPECT". Duplicated publications and studies regarding PD, atypical parkinsonisms, dystonia-parkinsonism, essential tremor, and parkinsonism due to non-degenerative causes were excluded.

resultsThe obtained results were reviewed and summarized, including DaTSCAN findings in fragile X-associated tremor/ataxia syndrome, prion diseases, Huntington's disease, spinocerebellar ataxia, hereditary spastic paraparesis, metabolic disorders, and other diseases (anti-IgLON5 disease, ring chromosome 20 syndrome, chorea-acanthocytosis, and neuronal ceroid lipofuscinosis).

conclusionsThis review highlights the need to determine in the future the utility and cost-effectiveness of DaTSCAN, both as a diagnostic and a prognostic tool, in patients with parkinsonian symptoms in rare neurodegenerative diseases.

Indexed as

Parkinsonian DisordersTomography, Emission-Computed, Single-PhotonHumansParkinson DiseaseTropanes2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropaneTropanesDaTSCANnigrostriatal pathwayParkinsonismSPECT

Identifiers

PMID38693679
PMCPMC11145110
OpenAlexW4396588593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.