Evidence map›Paper›PMID 38693444›Full record

ArticleWorld journal of urology2024

Prostate biopsy sepsis prevention: external validation of an alcohol needle washing protocol.

Anthony Hiffa, Merry Chen, Faizan Boghani, Michael D Oberle, W Carter Reed, Sherita A King, John De Caro, Martha K Terris, Matthew N Simmons, Thomas E Dykes

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anthony HiffaDepartment of Urology, Medical College of Georgia, Augusta University, 1120 15th Street, Urology B8417, Augusta, GA, 30912, USA.
Merry ChenDepartment of Urology, Medical College of Georgia, Augusta University, 1120 15th Street, Urology B8417, Augusta, GA, 30912, USA.
Faizan BoghaniDepartment of Urology, Medical College of Georgia, Augusta University, 1120 15th Street, Urology B8417, Augusta, GA, 30912, USA.
Michael D OberleDepartment of Urology, Medical College of Georgia, Augusta University, 1120 15th Street, Urology B8417, Augusta, GA, 30912, USA.
W Carter ReedDepartment of Urology, Medical College of Georgia, Augusta University, 1120 15th Street, Urology B8417, Augusta, GA, 30912, USA.
Sherita A KingDepartment of Urology, Medical College of Georgia, Augusta University, 1120 15th Street, Urology B8417, Augusta, GA, 30912, USA.
John De CaroCharlie Norwood Veterans' Affairs Medical Center, Augusta, GA, USA.
Martha K TerrisDepartment of Urology, Medical College of Georgia, Augusta University, 1120 15th Street, Urology B8417, Augusta, GA, 30912, USA.
Matthew N SimmonsDepartment of Urology, Medical College of Georgia, Augusta University, 1120 15th Street, Urology B8417, Augusta, GA, 30912, USA. msimmons@stanfordalumni.org.ORCID http://orcid.org/0000-0002-1504-1652
Thomas E DykesCharlie Norwood Veterans' Affairs Medical Center, Augusta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTransrectal ultrasound-guided prostate biopsy (TRUS-Bx) is associated with a 1-8% risk of post-biopsy sepsis (PBS). A recent study described an isopropyl alcohol needle washing protocol that significantly decreased PBS rates. The current study examined the efficacy of this technique in our clinic population. MATERIALS AND

methodsData were reviewed for 1250 consecutive patients undergoing TRUS-Bx at the Charlie Norwood VA Medical Center from January 2017 to January 2023. Needle washing was adopted in February 2021. Complications occurring within 30 days after TRUS-Bx were recorded.

resultsThere were 912 patients in group 1 (without needle washing) and 338 in group 2 (with needle washing). Groups had equivalent demographic features, and men of African descent comprised 70% of patients. Standard 12 core biopsies were done in 83% and 82% in groups 1 and 2, respectively (p = 0.788). Total complication rates were 4% and 2% in groups 1 and 2, respectively (p = 0.077). There were 13 sepsis events in group 1 (1.4%) and none in group 2 (p = 0.027). Clavien-Dindo Grade I-III complications occurred in 25 (2.7%) and 7 (2.1%) patients in groups 1 and 2, respectively (p = 0.505). Standard antibiotic prophylaxis (PO fluoroquinolone and IM gentamicin) was given in 80% and 86% of patients in groups 1 and 2, respectively (p = 0.030). Subset analysis limited to patients who received standard prophylaxis showed a significant difference in sepsis rates (1.5% vs 0%; p = 0.036).

conclusionsAdoption of isopropyl alcohol needle washing was associated with a significant decrease in PBS events.

Indexed as

2-PropanolImage-Guided BiopsyProstateSepsisAgedHumansMaleMiddle AgedNeedlesPostoperative ComplicationsProstatic NeoplasmsRetrospective StudiesUltrasonography, Interventional2-PropanolNeedle washingProstate biopsySepsis

Identifiers

PMID38693444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.