Evidence map›Paper›PMID 38693352›Full record

ArticleScientific reports2024

Comparing the clinical applicability of wavefront phase imaging in keratoconus versus normal eyes.

Carolina Belda-Para, Gonzalo Velarde-Rodríguez, Miriam Velasco-Ocaña, Juan M Trujillo-Sevilla, Iván Rodríguez-Méndez, Javier Rodríguez-Martin, Nicolas Alejandre-Alba, Silvia Rodríguez-García, José M Rodríguez-Ramos

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carolina Belda-ParaWooptix S.L., Avenida Trinidad, 61 Planta 7, 38000, La Laguna, Tenerife, Canary Islands, Spain. carolina@wooptix.com.
Gonzalo Velarde-RodríguezOphthalmology Department, Fundación Jiménez Díaz University Hospital, Avenida. Reyes Católicos 2, 28040, Madrid, Spain.
Miriam Velasco-OcañaWooptix S.L., Avenida Trinidad, 61 Planta 7, 38000, La Laguna, Tenerife, Canary Islands, Spain.
Juan M Trujillo-SevillaWooptix S.L., Avenida Trinidad, 61 Planta 7, 38000, La Laguna, Tenerife, Canary Islands, Spain.
Iván Rodríguez-MéndezWooptix S.L., Avenida Trinidad, 61 Planta 7, 38000, La Laguna, Tenerife, Canary Islands, Spain.
Javier Rodríguez-MartinClinica Nivaria, Avda. Reyes Católicos, 25, Tenerife, Canary Islands, Spain.
Nicolas Alejandre-AlbaOphthalmology Department, Fundación Jiménez Díaz University Hospital, Avenida. Reyes Católicos 2, 28040, Madrid, Spain.
Silvia Rodríguez-GarcíaUniversity of La Laguna, Calle Padre Herrera s/n, 38200, La Laguna, Tenerife, Canary Islands, Spain.
José M Rodríguez-RamosWooptix S.L., Avenida Trinidad, 61 Planta 7, 38000, La Laguna, Tenerife, Canary Islands, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this work is to quantitatively assess the wavefront phase of keratoconic eyes measured by the ocular aberrometer t·eyede (based on WaveFront Phase Imaging Sensor), characterized by a lateral resolution of 8.6 µm without requiring any optical element to sample the wavefront information. We evaluated the parameters: root mean square error, Peak-to-Valley, and amplitude of the predominant frequency (Fourier Transform analysis) of a section of the High-Pass filter map in keratoconic and healthy cohorts. Furthermore, we have analyzed keratoconic eyes that presented dark-light bands in this map to assess their period and orientation with the Fourier Transform. There are significant statistical differences (p value < 0.001) between healthy and keratoconic eyes in the three parameters, demonstrating a tendency to increase with the severity of the disease. Otherwise, the quantification of the bands reveals that the width is independent of eye laterality and keratoconic stage as orientation, which tends to be oblique. In conclusion, the quantitative results obtained with t·eyede could help to diagnose and monitor the progression of keratoconus.

Indexed as

KeratoconusAberrometryAdultCorneaCorneal TopographyFemaleFourier AnalysisHumansMaleYoung Adult

Identifiers

PMID38693352
PMCPMC11063207

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.