Evidence map›Paper›PMID 38693318›Full record

ArticleThe patient2024

Optimizing Communication on HPV Vaccination to Parents of 11- to 14-Year-Old Adolescents in France: A Discrete Choice Experiment.

Sandra Chyderiotis, Jonathan Sicsic, Amandine Gagneux-Brunon, Jocelyn Raude, Anne-Sophie Barret, Sébastien Bruel, Aurélie Gauchet, Anne-Sophie Le Duc Banaszuk, Morgane Michel, Bruno Giraudeau and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The patient, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Sandra ChyderiotisInstitut Pasteur, Université Paris Cité, Emerging Disease Epidemiology Unit, 75015, Paris, France.
Jonathan SicsicUniversité Paris Cité, LIRAES, 75006, Paris, France.
Amandine Gagneux-BrunonCHU de Saint-Etienne-Service d'Infectiologie, Saint-Etienne, France.
Jocelyn RaudeUniv. Rennes, EHESP, CNRS, Inserm, Arènes-UMR 6051, RSMS (Recherche sur les Services et Management en Santé)-U1309, 35000, Rennes, France.
Anne-Sophie BarretSanté Publique France, Saint-Maurice, France.
Sébastien BruelDepartment of General Practice, Jacques Lisfranc Faculty of Medicine, Saint-Etienne-Lyon University, Saint-Etienne, France.
Aurélie GauchetUniversité Savoie Mont Blanc, Univ. Grenoble Alpes, LIP/PC2S, 73000, Chambéry, France.
Anne-Sophie Le Duc BanaszukCentre Régional de Coordination des Dépistages des cancers-Pays de la Loire, 5 Rue des Basses Fouassières, 49000, Angers, France.
Morgane MichelUniversité Paris Cité, ECEVE, UMR 1123, Inserm, 75010, Paris, France.
Bruno GiraudeauUniversité de Tours, Université de Nantes, INSERM, SPHERE U1246, INSERM CIC 1415, CHRU de Tours, Tours, France.
Nathalie ThillyUniversité de Lorraine, APEMAC, 54500, Nancy, France.
Judith E MuellerInstitut Pasteur, Université Paris Cité, Emerging Disease Epidemiology Unit, 75015, Paris, France. Judith.mueller@ehesp.fr.ORCID 0000-0003-0797-9971
PrevHPV Consortium
Centre National de la Recherche Scientifique · FRUniversité Claude Bernard Lyon 1 · FRCentre d’Investigation Clinique Innovation Technologique de Nancy · FRCentre Pays de la Loire · FRInserm · FRInstitut Pasteur · FRSanté Publique France · FRUniversité de Tours · FRUniversité Paris Cité · FRUniversité Savoie Mont Blanc · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the aim to optimize communication during HPV vaccination campaigns in France, we elicited parental preferences around HPV vaccination.

methodsWe conducted a single-profile discrete choice experiment (DCE) among parents of 11- to 14-year-old middle-school pupils, who completed an anonymous, self-administered, internet-based questionnaire during 2020-2021. The DCE comprised five attributes (vaccine-preventable disease, justification of optimal age, information on safety, indirect protection and coverage) of vaccination against an unnamed disease that were presented to respondents in ten choice tasks, or scenarios. We use fixed effect logit models to estimate attribute weights on theoretical vaccine acceptance, and random effect linear regression to estimate attribute coefficients on vaccine eagerness (decision and decision certainty). We estimated marginal effects of attributes on expected vaccine acceptance.

resultsVaccination scenarios were accepted by 55.6-89.2% of the 1291 participants. The largest marginal effects on expected vaccine acceptance in the full sample arose from prevention of cancer versus genital warts (+ 11.3 percentage points); from a "severe side effect suspicion that was not scientifically confirmed" versus a statement about "more benefits than risks" (+ 8.9 percentage points), and information on 80% vaccine coverage in neighbouring countries versus on "insufficient coverage" (+ 4.2 percentage points). Explaining the early age of vaccination by sexual debut had a strong negative impact among French monolingual parents with lower education level (vs age-independent, OR 0.48, 95% CI 0.27-0.86), but not other socio-economic groups. After removing low-quality responses (unvaried certainty and short questionnaire completion), among serial non-demanders with children not vaccinated against HPV, only disease elimination impacted vaccine eagerness positively (coefficient 0.54, 0.06-1.02). DISCUSSION: Using DCEs to elicit parents' preferences around communication messages, notably on cancer prevention, vaccine coverage and information about vaccine safety, could help to optimize HPV vaccination promotion efforts.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesParentsAdolescentAdultChildChoice BehaviorCommunicationFemaleFranceHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedPatient Acceptance of Health CareSurveys and QuestionnairesPapillomavirus Vaccines

Identifiers

PMID38693318
PMCPMC11343910
OpenAlexW4396541821

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.