ArticleNature2024
Airway hillocks are injury-resistant reservoirs of unique plastic stem cells.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
25.4field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
47 citing papers in PubMed, 58 citations in OpenAlex.
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 3 countries.
Brian Lin *Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA. brian.lin@tufts.edu.ORCID 0000-0002-8851-3534
Viral S Shah *Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Chaim Chernoff *Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-9459-1240
Jiawei SunCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Gergana G ShipkovenskaCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Vladimir VinarskyCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Avinash WaghrayCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Jiajie XuCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Andrew D LeducDepartment of Bioengineering, Northeastern University, Boston, MA, USA.
Constantin A HintschichDepartment of Developmental, Molecular and Chemical Biology, School of Medicine, Tufts University, Boston, MA, USA.
Manalee Vishnu SurveCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Yanxin XuCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Diane E CapenProgram in Membrane Biology and Nephrology Division, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-7254-788X
Jorge VilloriaCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
Zhixun DouCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-3069-3907
Lida P HaririDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Jayaraj RajagopalCenter for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA. jrajagopal@mgh.harvard.edu.ORCID 0000-0002-4122-177X
Massachusetts General Hospital · USBroad Institute · USTufts University · USHarvard University · USHarvard University Press · USNortheastern University · US
Funding
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Ramnik J Xavier · 1991 to 2026
$35.3MTransgenic CoreP30DK057521 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BROWN, DENNIS · 2000 to 2019
$31.4MThe LungMAP Data Coordination Center for Next Gen Systems Biology of RespirationU24HL148865 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Bruce J Aronow, Nathan G. Salomonis · 2019 to 2026
$12.4MResearch Training in Pulmonary Immunology and Allergy at MGHT32HL116275 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI David C Christiani, ANDREW D LUSTER · 2013 to 2026
$8.6MP&F programP30DK135043 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Dennis Brown · 2023 to 2026
$5.4MIntercellular communication and cell regulation in airway epithelial ensembles in regeneration and diseaseR01HL118185 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI RAJAGOPAL, JAYARAJ · 2014 to 2021
$4.2MLive Imaging of Intact AirwayR01HL142559 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LIN, CHARLES P., RAJAGOPAL, JAYARAJ · 2018 to 2021
$2.2MSingle-cell proteomic identification of novel markers of senescenceUH3CA268117 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DOU, ZHIXUN, RAJAGOPAL, JAYARAJ · 2023 to 2024
$1.9MDefining the lineage, mechanisms of maintenance, and function of a new injury-resistant airway epithelial structure: the hillockR01HL157221 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI RAJAGOPAL, JAYARAJ · 2022 to 2025
$1.9MSingle-cell proteomic identification of novel markers of senescenceUG3CA268117 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DOU, ZHIXUN, RAJAGOPAL, JAYARAJ · 2021 to 2022
$1.2MRe-establishment of directional mucociliary transport after epithelial injuryK08HL124298 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI VINARSKY, VLADIMIR · 2014 to 2018
$796kThe Hillock: A Newly Discovered Airway Epithelial Structure and its Relationship with Squamous MetaplasiaF31HL165736 · NHLBI · HARVARD MEDICAL SCHOOL · PI CHERNOFF, CHAIM ZEV · 2023 to 2025
$119kNCI NIH HHS UG3 CA268117NCI NIH HHS UH3 CA268117NHLBI NIH HHS F31 HL165736NHLBI NIH HHS K08 HL124298NHLBI NIH HHS R01 HL118185NHLBI NIH HHS R01 HL142559NHLBI NIH HHS R01 HL157221NHLBI NIH HHS T32 HL116275NHLBI NIH HHS U24 HL148865NIDDK NIH HHS P30 DK043351NIDDK NIH HHS P30 DK057521NIDDK NIH HHS P30 DK135043
Abstract
Airway hillocks are stratified epithelial structures of unknown function
Indexed as
Cell PlasticityEpithelial CellsRegenerationRespiratory MucosaStem CellsAnimalsFemaleHumansLung NeoplasmsMaleMetaplasiaMiceMice, Inbred C57BLTretinoinVitamin ATretinoinVitamin A
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.