Evidence map›Paper›PMID 38692309›Full record

ArticlePreventive medicine2024

Perceptions about doxycycline post-exposure prophylaxis (Doxy-PEP) as an STI-prevention strategy among gay and bisexual men (GBM) in the United States: Results from a qualitative study.

Rifa Ehsan, Alexa B D'Angelo, Drew A Westmoreland, Christian Grov

Open access · greenAbstract read
In one paragraph

Article in Preventive medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Perceptions of DoxyPEP use Among Racial & Ethnic Minority Patients.Journal of racial and ethnic health disparities · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Doxycycline post-exposure prophylaxis (doxyPEP): balancing promise and prudence in the prevention of sexually transmitted infections.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rifa EhsanCUNY Institute for Implementation Science in Population Health, New York, NY, USA; CUNY Graduate School of Public Health and Health Policy, New York, NY, USA.
Alexa B D'AngeloCUNY Institute for Implementation Science in Population Health, New York, NY, USA; CUNY Graduate School of Public Health and Health Policy, New York, NY, USA.
Drew A WestmorelandCollege of Medicine & College of Public health and Health Professions, University of Florida, Gainesville, FL, USA; Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, USA.
Christian GrovCUNY Institute for Implementation Science in Population Health, New York, NY, USA; CUNY Graduate School of Public Health and Health Policy, New York, NY, USA. Electronic address: Christian.Grov@sph.cuny.edu.
The Graduate Center, CUNY · USUniversity of Florida · US

Funding

Patient and Population Health Outcomes Research SWGP30AI124414 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Joan Weinberger Berman · 2017 to 2026
$28.3M
Following a U.S. National Cohort of Vulnerable Men to Improve HIV Prevention and CareUH3AI133675 · NIAID · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI GROV, CHRISTIAN · 2019 to 2021
$6.9M
Following a U.S. National Cohort of Vulnerable Men to Improve HIV Prevention and CareUG3AI133675 · NIAID · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI GROV, CHRISTIAN · 2017 to 2018
$2.6M
The Impact of Alcohol on PrEP Adherence in Vulnerable MenK01AA029047 · NIAAA · UNIVERSITY OF FLORIDA · PI WESTMORELAND, DREW ANNE · 2020 to 2024
$940k
NIAAA NIH HHS K01 AA029047NIAAA NIH HHS L60 AA030435NIAID NIH HHS P30 AI124414NIAID NIH HHS UG3 AI133675NIAID NIH HHS UH3 AI133675
6 · The paper itself

Abstract

objectiveTo leverage qualitative data to explore gay and bisexual men's (GBM) perceptions about doxycycline post-exposure prophylaxis (Doxy-PEP). Doxy-PEP is a novel biomedical STI-prevention strategy that helps reduce the risk of acquiring bacterial STIs. Little is known about Doxy-PEP's acceptability in the U.S., nor how best to engage those most vulnerable to STIs in taking up this nascent prevention strategy.

methodBetween July and September of 2023, 24 GBM from across the U.S. completed qualitative interviews about their perceptions regarding Doxy-PEP. Interviews were analyzed using a codebook approach to thematic analysis.

resultsParticipants were generally interested in using Doxy-PEP, but were concerned about the potential for antibiotic resistance, side-effects, medication interactions to occur, along with stigmatizing discourse around its use. Meanwhile, participants were motivated by the simplicity of Doxy-PEP and the protection it could confer on both an individual and community-level- as well as its potential to reduce STI-related anxiety. Finally, participants desired additional information on Doxy-PEP to address their concerns.

conclusionsThere is a need for clear guidelines and expanded public health messaging on Doxy-PEP in the U.S.

Indexed as

DoxycyclineHomosexuality, MalePost-Exposure ProphylaxisQualitative ResearchSexual and Gender MinoritiesAdultAnti-Bacterial AgentsHumansInterviews as TopicMaleMiddle AgedPerceptionSexually Transmitted DiseasesUnited StatesAnti-Bacterial AgentsDoxycyclineBisexual menDoxy-PEPGay menSexually transmitted infectionsSTI-prevention

Identifiers

PMID38692309
PMCPMC11148872
OpenAlexW4396217687

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.