Evidence map›Paper›PMID 38692162›Full record

ArticleJournal of psychiatric research2024

Not missing at random: Missing data are associated with clinical status and trajectories in an electronic monitoring longitudinal study of bipolar disorder.

Ramzi Halabi, Benoit H Mulsant, Martin Alda, Alexandra DeShaw, Arend Hintze, Muhammad I Husain, Claire O'Donovan, Rachel Patterson, Abigail Ortiz

Open access · hybridAbstract read
In one paragraph

Article in Journal of psychiatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Ramzi HalabiCampbell Family Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.
Benoit H MulsantCampbell Family Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Martin AldaDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada; National Institute of Mental Health, Klecany, Czech Republic.
Alexandra DeShawNova Scotia Health Authority, Halifax, Nova Scotia, Canada.
Arend HintzeDepartment of MicroData Analytics, Dalarna University, Sweden.
Muhammad I HusainCampbell Family Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Claire O'DonovanDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Rachel PattersonCampbell Family Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.
Abigail OrtizCampbell Family Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address: Abigail.ortiz@utoronto.ca.
Centre for Addiction and Mental Health · CADalhousie University · CADalarna University · SENova Scotia Health Authority · CA

Funding

Multimodal monitoring and high-dimensional data for episode prediction in bipolar disorderR21MH123849 · NIMH · CENTRE FOR ADDICTION AND MENTAL HEALTH · PI ORTIZ, ABIGAIL · 2021 to 2022
$262k
CIHRNIMH NIH HHS R21 MH123849
6 · The paper itself

Abstract

There is limited information on the association between participants' clinical status or trajectories and missing data in electronic monitoring studies of bipolar disorder (BD). We collected self-ratings scales and sensor data in 145 adults with BD. Using a new metric, Missing Data Ratio (MDR), we assessed missing self-rating data and sensor data monitoring activity and sleep. Missing data were lowest for participants in the midst of a depressive episode, intermediate for participants with subsyndromal symptoms, and highest for participants who were euthymic. Over a mean ± SD follow-up of 246 ± 181 days, missing data remained unchanged for participants whose clinical status did not change throughout the study (i.e., those who entered the study in a depressive episode and did not improve, or those who entered the study euthymic and remained euthymic). Conversely, when participants' clinical status changed during the study (e.g., those who entered the study euthymic and experienced the occurrence of a depressive episode), missing data for self-rating scales increased, but not for sensor data. Overall missing data were associated with participants' clinical status and its changes, suggesting that these are not missing at random.

Indexed as

Bipolar DisorderAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedSelf ReportYoung Adult

Identifiers

PMID38692162
PMCPMC11295604
OpenAlexW4395085659

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.