Evidence map›Paper›PMID 38691826›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Early Mortality in Clinical Trials of Acute Respiratory Distress Syndrome.

Vassilis G Giannakoulis, Edward J Schenck, Eleni Papoutsi, David R Price, Jesús Villar, Hina Sarwath, Frank Schmidt, B Taylor Thompson, Augustine M K Choi, Ilias I Siempos

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Relative contribution of driving pressure and respiratory rate to mortality in ARDS depends on age.American journal of respiratory and critical care medicine · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vassilis G GiannakoulisFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Edward J SchenckDivision of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0002-7950-5989
Eleni PapoutsiFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.
David R PriceDivision of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0002-0235-9450
Jesús VillarCentro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
Hina SarwathProteomics Core, Weill Cornell Medicine-Qatar, Qatar Foundation, Doha, Qatar; and.
Frank SchmidtProteomics Core, Weill Cornell Medicine-Qatar, Qatar Foundation, Doha, Qatar; and.
B Taylor ThompsonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Augustine M K ChoiDivision of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Ilias I SiemposFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.ORCID 0000-0003-0036-3322

Funding

The Role of HEME Oxygenase in Hyperoxic Lung InjuryR01HL055330 · NHLBI · YALE UNIVERSITY · PI CHOI, AUGUSTINE M, CHOI, MARY E · 1998 to 2021
$6.6M
Necroinflammatory Cell Death in SepsisK23HL151876 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHENCK, EDWARD JAMES · 2021 to 2025
$975k
Protective role of Endothelial Receptor Interacting Protein Kinase 3 (RIPK3) in acute lung injuryK08HL166958 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI DAVID REGAN PRICE · 2024 to 2026
$507k
Hellenic Foundation for Research and Innovation 80- 1/15.10.2020Hellenic Thoracic Society 2023NHLBI NIH HHS K08 HL166958NHLBI NIH HHS K23 HL151876NHLBI NIH HHS R01 HL055330NHLBI NIH HHS R01 HL055330-20
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Respiratory Distress SyndromeClinical Trials as TopicFemaleHumansMaleMiddle Aged

Identifiers

PMID38691826
PMCPMC11273316

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.