Evidence map›Paper›PMID 38691612›Full record

ArticleScience advances2024

Highly stretchable and customizable microneedle electrode arrays for intramuscular electromyography.

Qinai Zhao, Ekaterina Gribkova, Yiyang Shen, Jilai Cui, Noel Naughton, Liangshu Liu, Jaemin Seo, Baixin Tong, Mattia Gazzola, Rhanor Gillette and 1 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
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  10. Article
  11. Review
  12. Article
  13. Cell-Stress-Free Percutaneous Bioelectrodes.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  14. Review
  15. Article
  16. Wearable Bioelectronics for Home-Based Monitoring and Treatment of Muscle Atrophy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  17. Review
  18. Review
  19. Electrical Microneedles for Wound Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Qinai ZhaoDepartment of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-2922-8135
Ekaterina GribkovaNeuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Yiyang ShenCenter for Advanced Manufacturing, University of Southern California, Los Angeles, CA, USA.
Jilai CuiNeuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0002-4001-1092
Noel NaughtonDepartment of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0002-5553-4718
Liangshu LiuDepartment of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0001-6656-7323
Jaemin SeoDepartment of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-2941-9521
Baixin TongCenter for Advanced Manufacturing, University of Southern California, Los Angeles, CA, USA.
Mattia GazzolaDepartment of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0003-2129-379X
Rhanor GilletteNeuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0001-7428-6214
Hangbo ZhaoDepartment of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0001-5229-4192
University of Southern California · USUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stretchable three-dimensional (3D) penetrating microelectrode arrays have potential utility in various fields, including neuroscience, tissue engineering, and wearable bioelectronics. These 3D microelectrode arrays can penetrate and conform to dynamically deforming tissues, thereby facilitating targeted sensing and stimulation of interior regions in a minimally invasive manner. However, fabricating custom stretchable 3D microelectrode arrays presents material integration and patterning challenges. In this study, we present the design, fabrication, and applications of stretchable microneedle electrode arrays (SMNEAs) for sensing local intramuscular electromyography signals ex vivo. We use a unique hybrid fabrication scheme based on laser micromachining, microfabrication, and transfer printing to enable scalable fabrication of individually addressable SMNEA with high device stretchability (60 to 90%). The electrode geometries and recording regions, impedance, array layout, and length distribution are highly customizable. We demonstrate the use of SMNEAs as bioelectronic interfaces in recording intramuscular electromyography from various muscle groups in the buccal mass of

Indexed as

ElectromyographyMicroelectrodesNeedlesAnimalsElectrodesEquipment DesignHumansMuscle, Skeletal

Identifiers

PMID38691612
PMCPMC11062587
OpenAlexW4396541836

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.