ArticleCell reports2024
Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation.
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Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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0cells of the map it votes in
36citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
What it found
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Who cites it
36 citing papers in PubMed, 33 citations in OpenAlex.
- Article
- Virtual screening and experimental validation of a METTL3-targeting peptide withJournal of enzyme inhibition and medicinal chemistry · 2026Article
- Targeting MYC-Driven Cancers: From Oncogenic Addiction to Therapeutic Vulnerability.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026Review
- The Role of NMedComm · 2026Review
- METTL3-mediated mJournal of translational medicine · 2026Article
- RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition.Cell death & disease · 2026Article
- Epigenetic regulation in cancer metastasis.Discover oncology · 2026Review
- Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte-Macrophage Crosstalk.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Epitranscriptomic Regulation of Platinum Resistance via the METTL3-ADAM23 Axis in Ovarian Cancer.Cells · 2026Article
- Advances in multi-omics research on neuroblastoma.Frontiers in pediatrics · 2026Review
- m6A-Targeted Cancer Therapy: Molecular Targets, Inhibitors, and Nanodelivery Strategies.International journal of nanomedicine · 2026Review
- mRNA processing in cancer immunotherapy: emerging targets, resistance mechanisms, and therapeutic opportunities.Frontiers in immunology · 2026Review
- The METTL3-YTHDC1 axis mediates architectural RNA mMolecular cancer · 2025Article
- Deciphering the interplay between SETD2 mediated H3K36me3 and RNA N6-methyladenosine in clear cell renal cell carcinoma (ccRCC).Epigenetics · 2025Article
- HOTAIR requires epitranscriptomic modification to exert its pivotal epigenetic role in Epithelial to Mesenchymal Transition.Cell death & disease · 2025Article
- Integrating machine learning and protein-ligand interaction profiling for the discovery of METTL3 inhibitors.Scientific reports · 2025Article
- m6A modification of non‑coding RNA: Mechanisms, functions and potential values in human diseases (Review).International journal of molecular medicine · 2025Review
- Rethinking RNA Modifications: Therapeutic Strategies for Targeting Dysregulated RNA.Journal of molecular biology · 2025Review
- Role of m6A RNA methylation regulators in pancreatic cancer: interactions and potential implications.Cancer cell international · 2025Review
- Dynamic modifications of circular RNAs drive oncogenesis.Epigenomics · 2025Review
Corrections and comments
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Authors and funding
21 authors at 5 institutions in 2 countries.
Monica PomavilleDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
Mohansrinivas ChennakesavaluDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
Pingluan WangDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Zhiwei JiangDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Hui-Lung SunDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Peizhe RenDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Ryan BorchertDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
Varsha GuptaDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
Chang YeDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Ruiqi GeDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Zhongyu ZhuDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Mallory BrodnikDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
Yuhao ZhongDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Kelley MooreDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
Helen SalwenDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
Rani E GeorgeDepartment of Pediatric Hematology/Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Malgorzata KrajewskaSchool of Biochemistry and Cell Biology, Biosciences Institute, University College Cork, Cork, Ireland.
Alexandre ChlenskiDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
Mark A ApplebaumDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
Chuan HeDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, University of Chicago, Chicago, Il 60637 USA.
Susan L CohnDepartment of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA. Electronic address: scohn@bsd.uchicago.edu.
Comer Children's Hospital · USUniversity of Chicago · USDana-Farber Cancer Institute · USHoward Hughes Medical Institute · USUniversity College Cork · IE
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MVIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI CHIEN-MIN KAO · 1985 to 2026
$122.1MTranscriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4MHoward Hughes Medical InstituteNCI NIH HHS P30 CA008748NCI NIH HHS P30 CA014599NHGRI NIH HHS RM1 HG008935
Abstract
The N
Indexed as
Cell DifferentiationCell ProliferationMethyltransferasesNeuroblastomaAdenosineAnimalsCell Line, TumorGene Expression Regulation, NeoplasticHumansMiceAdenosineMethyltransferasesMETTL14 protein, humanMETTL3 protein, humanN-methyladenosineCP: Cancerdifferentiationepitranscriptomegene expression regulationm(6)Aneuroblastomatherapeutic targettumor growth
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.