Evidence map›Paper›PMID 38691155›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Comparison of emotional and behavioral regulation between metopic and sagittal synostosis.

Mariana N Almeida, David P Alper, Neil Parikh, Heloise De Baun, Alex Kammien, John A Persing, Michael Alperovich

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Daily executive function in children and adolescents with non-syndromic craniosynostosis: association with timing of surgical intervention.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  2. Cognitive and neuropsychomotor development in craniosynostosis: an evaluation of the most affected functions.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Observational
  3. Comparison of behavioral outcomes following cranial vault remodeling versus strip craniectomy for non-syndromic sagittal craniosynostosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mariana N AlmeidaDivision of Plastic Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.
David P AlperDivision of Plastic Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.
Neil ParikhDivision of Plastic Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.
Heloise De BaunRenaissance School of Medicine at Stony, Brook University, Stony Brook, NY, USA.
Alex KammienDivision of Plastic Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.
John A PersingDivision of Plastic Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.
Michael AlperovichDivision of Plastic Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA. Michael.alperovich@yale.edu.
Yale University · USStony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChildren with surgically corrected nonsyndromic craniosynostosis have been previously found to have neurocognitive and behavioral difficulties. Children with metopic synostosis have been described to have more difficulties than children with sagittal synostosis. This study aims to characterize the behavioral differences between children with metopic and sagittal synostosis.

methodsChildren with metopic and sagittal synostosis were recruited at school age. Parents completed four separated behavioral assessments: Conners-3 (evaluation of ADHD), Social Responsiveness Scale-2 (SRS-2: evaluation of autism), Behavior Rating Inventory of Executive Function-2 (BRIEF-2: evaluation of executive function), and Child Behavior Checklist (CBCL: evaluation of overall behavioral problems). Children underwent intelligence quotient (IQ) testing using the Wechsler Abbreviated Scale of Intelligence (WASI-II).

resultsThere were 91 children (45 with metopic and 46 with sagittal synostosis). More children with metopic synostosis reported requiring supportive services (57.7% vs 34.7%, p = 0.02) and more reached or exceeded borderline clinical levels of two executive function subscales of the BRIEF-2 (emotion regulation index: 33.3% vs 17.4%, p = 0.05; global executive composite: 33.3% vs 17.4%, p = 0.05). Children with sagittal synostosis had higher scores on the rule-breaking and externalizing problem subscales of the CBCL. Increasing age at surgery was associated with worse executive function scores.

conclusionsA relationship between suture subtype and behavioral outcomes exists at school age. More children with metopic synostosis required social services indicating more overall difficulties. Children with metopic synostosis have more specific problems with executive function, while children with sagittal synostosis had more difficulties with externalizing behaviors.

Indexed as

CraniosynostosesChildChild BehaviorEmotional RegulationExecutive FunctionFemaleHumansMaleBehaviorMetopicNonsyndromic craniosynostosisOutcomesSagittal

Identifiers

PMID38691155
OpenAlexW4396547520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.