ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2024
The utility of serum glucose potassium ratio as a predictive factor for haemorrhagic transformation, stroke recurrence, and mortality among ischemic stroke patients.
Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Cannabinoids on Ischemic Stroke-Associated Neuroinflammation: A Systematic Review.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025Pooled it
- Electrolyte-derived clinical indices in traumatic brain injury: A narrative review.World journal of methodology · 2026Review
- Glucose/potassium ratio and a novel combined model for the differential diagnosis of testicular torsion: a retrospective study.Basic and clinical andrology · 2026Article
- Dynamic Changes in Endothelial Glycocalyx and Inflammatory Response in Patients with Acute Ischemic Stroke Treated with Mechanical Thrombectomy: Pathophysiological Aspects and Clinical Implications.Neurology international · 2026Review
- Predictive value of blood composite biomarkers for hemorrhagic transformation following mechanical thrombectomy in acute anterior circulation large vessel occlusion stroke patients.Frontiers in neuroscience · 2026Article
- Predictive value of serum homocysteine and potassium ion for short-term prognosis of patients with acute cerebral infarction following intravenous thrombolysis with recombinant tissue plasminogen activator.Thrombosis journal · 2025Article
- Evaluation of the predictive value of the glucose-to-potassium ratio in predicting in-hospital mortality of patients with sepsis and septic shock.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Observational
- U shaped relationship between serum glucose potassium ratio and mortality in critically ill patients with toxic encephalopathy.Scientific reports · 2025Article
- Role of serum glucose/potassium ratio in assessing poisoning severity and adverse outcomes in patients with acute aluminum phosphide poisoning.Toxicology reports · 2025Article
- Comparison between pediatric and adult acute natural cannabinoids toxicity: A 5-year retrospective study with special consideration of acute synthetic cannabinoids toxicity.Toxicology reports · 2025Article
- Effects of previous steroid treatment on ischemic stroke outcomes: a propensity score-matched hospital analysis.Frontiers in pharmacology · 2025Article
- Prognostic Value of Glucose-to-Potassium Ratio in Acute Ischemic Stroke Patients Undergoing Thrombolysis and Its Interaction with Inflammation.Clinical interventions in aging · 2025Article
- Association between serum glucose potassium ratio and short- and long-term all-cause mortality in patients with sepsis admitted to the intensive care unit: a retrospective analysis based on the MIMIC-IV database.Frontiers in endocrinology · 2025Article
- A multicenter analysis to identify the risk factors for stroke recurrence and mortality within 1 year.Frontiers in neurology · 2025Article
- Assessing the effects of antidepressant use on stroke recurrence and related outcomes in ischemic stroke patients: a propensity score matched analysis.Frontiers in pharmacology · 2025Article
- Post-stroke mortality in ICU patients with serum glucose-potassium ratio: an analysis of MIMIC-IV database.Frontiers in neurology · 2025Article
- Insights into risk factors and outcomes of post-stroke seizures in Saudi Arabia: a multicenter analysis.Metabolic brain disease · 2024Observational
- Association between serum glucose potassium ratio and mortality in critically ill patients with intracerebral hemorrhage.Scientific reports · 2024Article
- Role of the Stress Index in Predicting Mortality among Patients with Traumatic Femoral Fractures.Diagnostics (Basel, Switzerland) · 2024Article
- The Stress Index as a Predictor of Mortality in Patients with Isolated Moderate to Severe Traumatic Brain Injury.Diagnostics (Basel, Switzerland) · 2024Article
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16 authors.
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Abstract
Background and Objective: Glucose-Potassium Ratio (GPR) has emerged as a biomarker in several pathophysiological conditions. However, the association between GPR and long-term outcomes in stroke patients has not been investigated. Our study evaluated the applicability of baseline GPR as a predictive prognostic tool for clinical outcomes in ischemic stroke patients. Methods: The multicenter retrospective cohort study included acute-subacute adult ischemic stroke patients who had their baseline serum GPR levels measured. Eligible patients were categorized into two sub-cohorts based on the baseline GPR levels (<1.67 vs. ≥ 1.67). The primary outcome was the incidence of 30-day hemorrhagic transformation, while stroke recurrence, and all-cause mortality within twelve months, were considered secondary. Results: Among 4083 patients screened, 1047 were included in the current study. In comparison with GPR < 1.67 group, patients with ≥ 1.67 GPR had a significantly higher ratio of all-cause mortality within twelve months (aHR 2.07 [95 % CI 1.21-3.75] Conclusion: Overall, baseline GPR serum is an independent predictor of all-cause mortality within twelve months in patients with acute and subacute ischemic stroke. Further clinical studies are necessary to validate these findings.
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