Trial reportJournal of pediatric orthopedics2024
Effectiveness of the Bilateral and Bilevel Erector Spinae Plane Block (ESPB) in Pediatric Idiopathic Scoliosis Surgery: A Randomized, Double-Blinded, Controlled Trial.
Trial report in Journal of pediatric orthopedics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Erector spinae plane block in pediatric surgery: a systematic review and meta-analysis.BMC anesthesiology · 2026Pooled it
- Safety and efficacy of erector spinae plane block for perioperative analgesia in posterior spinal fusion surgery for pediatric idiopathic scoliosis: a meta-analysis.Spine deformity · 2025Pooled it
- Erector spinae plane block reduces postoperative nausea and vomiting: a systematic review and meta-analysis of 44 randomized trials.Frontiers in medicine · 2025Pooled it
- Analgesic efficacy of bilateral erector spinae plane block in pediatric tethered cord syndrome surgery: a prospective, randomized controlled trial.Revista da Associacao Medica Brasileira (1992) · 2026Trial
- Dexamethasone as a perineural adjuvant to a ropivacaine popliteal sciatic nerve block for pediatric foot surgery: a randomized, double-blind, placebo-controlled trial.Regional anesthesia and pain medicine · 2025Trial
- Comparison of analgesic efficacy of erector spinae plane block at different levels in laparoscopic cholecystectomies: a randomized controlled trial.BMC anesthesiology · 2025Trial
- Erector spinae plane block (ESPB) vs. pericapsular nerve group (PENG) block in total hip arthroplasty in elderly patients: a randomized, double-blinded, controlled trial.Anaesthesiology intensive therapy · 2025Trial
- An Update on Pain Management in Pediatric Spine Surgery.Current reviews in musculoskeletal medicine · 2026Review
- Comment on: "Analgesic effects of bilateral ultrasound-guided erector spinae plane block versus patient-controlled intravenous analgesia in correction surgery for idiopathic scoliosis: study protocol for a randomized controlled trial".Perioperative medicine (London, England) · 2026Article
- The Modulatory Effects of Anesthetics and Analgesics on Neurophysiological Monitoring and Underlying Mechanisms.Current neuropharmacology · 2026Review
- Perioperative Anesthetic Management in Pediatric Scoliosis Surgery: A Narrative Review with Focus on Neuromuscular Disorders.Children (Basel, Switzerland) · 2025Review
- Article
- The Influence of Anesthesia on Neuromonitoring During Scoliosis Surgery: A Systematic Review.NeuroSci · 2024Review
- The Influence of Regional Anesthesia on the Systemic Stress Response.Reports (MDPI) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to compare the effect of the ultrasound-guided bilateral and bilevel erector spinae plane block (ESPB) on pain scores, opioid requirement, intraoperative motor-evoked potentials (MEPs), and stress response to surgery expressed by the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) versus standard analgesia methods following idiopathic scoliosis surgery.
methodsThis was a prospective, double-blinded, randomized controlled trial. Sixty patients aged 10 to 18 years and physical status ASA 1 or 2 were randomized into 2 equal groups, each receiving an ESPB or sham block. The primary outcome was the pain scores (Numerical Rating Scale, NRS) within 48 hours after spinal correction and fusion surgery for idiopathic thoracic scoliosis. The secondary outcomes were total opioid consumption, NLR, and PLR levels at 12 and 24 hours postoperatively and intraoperative MEPs.
resultsESPB patients presented lower NRS scores, signifying less pain, at all time points (30, 60, 90, 120 min; and 6, 12, 24, and 48 h after surgery), all P <0.0001. The total opioid consumption, the incidence of nausea or vomiting, and the need for remifentanil and propofol during surgery were significantly lower in the ESPB group. The surgery-induced stress response expressed by NLR and PLR was considerably lower in the ESPB group. ESPB did not affect the intraoperative MEP's amplitude.
conclusionsESPB is effective for postoperative analgesia, can reduce opioid consumption in patients undergoing scoliosis surgery, and reduces the stress response to surgery. ESPB does not interfere with neuromonitoring. LEVEL OF EVIDENCE: Level I.
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