Evidence map›Paper›PMID 38689370›Full record

ArticleDevelopmental psychobiology2024

Rhinorrhea and watery eyes in infancy and risk of attention-deficit hyperactivity disorder in school-age children.

Matthew S Perzanowski, Virginia Rauh, Bruce Ramphal, Luis Acosta, Lori Hoepner, Andrew G Rundle, Frederica P Perera, Julie Herbstman, Rachel L Miller, Amy E Margolis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental psychobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matthew S PerzanowskiDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA.
Virginia RauhDepartment of Population and Family Health, Mailman School of Public Health, Columbia University, New York, New York, USA.
Bruce RamphalDivision of Child and Adolescent Psychiatry, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Luis AcostaDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA.
Lori HoepnerData Coordinating Center, Columbia University, New York, New York, USA.
Andrew G RundleDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.
Frederica P PereraDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA.
Julie HerbstmanDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA.
Rachel L MillerDivision of Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Amy E MargolisDivision of Child and Adolescent Psychiatry, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA.ORCID 0000-0002-3334-6783

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
HEALTH EFFECTS OF PAH &ETS IN MINORITY WOMEN &NEWBORNSR01ES008977 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PERERA, FREDERICA P · 1997 to 2011
$12.9M
The Columbia Center for Children's Environmental HealthP01ES009600 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ANDREWS, HOWARD F. · 1999 to 2014
$11.2M
Windows of Susceptibility to PAH/DEP Exposure and AsthmaP50ES015905 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ANDREWS, HOWARD F. · 2007 to 2011
$10.3M
Urban Diesel Exposure and Inner City AsthmaR01ES013163 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, RACHEL L · 2005 to 2016
$6.5M
The Columbia Center for Children's Environmental HealthP50ES009600 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PETERSON, BRADLEY S · 2015 to 2018
$3.4M
Prenatal Environmental Mixtures, Cognitive Control and Reward Processes, And Risk for Psychiatric Problems in Adolescence.R01ES032296 · NIEHS · OHIO STATE UNIVERSITY · PI MARGOLIS, AMY · 2021 to 2025
$2.6M
Environmental bisphenol exposure, infant brain and behavior: Human and animal modelsR01ES030950 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI VEENSTRA-VANDERWEELE, JEREMY · 2020 to 2023
$2.6M
Prenatal Exposure to Environmental Tobacco Smoke, COVID-19- Related Psychosocial Stress, and Neurodevelopment.K23ES026239 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARGOLIS, AMY · 2016 to 2021
$767k
NIEHS NIH HHS K23 ES026239NIEHS NIH HHS K23ES026239NIEHS NIH HHS P01 ES009600NIEHS NIH HHS P01ES09600/RD83214101NIEHS NIH HHS P30 ES009089NIEHS NIH HHS P50 ES009600NIEHS NIH HHS P50 ES015905NIEHS NIH HHS P50ES015905NIEHS NIH HHS P50ES09600/R83615401NIEHS NIH HHS R01 ES008977NIEHS NIH HHS R01 ES013163NIEHS NIH HHS R01ES013163NIEHS NIH HHS R01 ES030950NIEHS NIH HHS R01ES030950NIEHS NIH HHS R01 ES032296NIEHS NIH HHS R01ES032296NIEHS NIH HHS R01ES08977
6 · The paper itself

Abstract

Increased parasympathetic nervous system (PNS) activity is associated with attention-deficit/hyperactivity disorder (ADHD) inattentive symptoms, but not hyperactive-impulsive symptoms, and may contribute to inattentive subtype etiology. Guided by prior work linking infant rhinorrhea and watery eyes without a cold (RWWC) to PNS dysregulation, we examined associations between infant RWWC and childhood ADHD symptoms in a longitudinal cohort of Black and Latinx children living in the context of economic disadvantage (N = 301 youth: 158 females, 143 males). Infant RWWC predicted higher inattentive (relative risk [RR] 2.16, p < .001) but not hyperactive-impulsive (RR 1.53, p = .065) ADHD symptoms (DuPaul scale), administered to caregivers at child age 8-14 years. Stratified analyses revealed that these associations were present in females but not males, who were three times more likely to have higher ADHD current total symptoms if they had infant RWWC than if they did not. Additionally, associations between RWWC and inattention symptoms were observed only in females. RWWC may thus serve as a novel risk marker of ADHD inattentive-type symptoms, especially for females.

Indexed as

Attention Deficit Disorder with HyperactivityAdolescentChildFemaleHispanic or LatinoHumansInfantLongitudinal StudiesMaleParasympathetic Nervous SystemSex Factorsasthmaattention‐deficit/hyperactivity disorderexercise‐induced wheezeinattentionparasympathetic nervous systemrhinitiswatery eyes

Identifiers

PMID38689370
PMCPMC12888088

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.