Evidence map›Paper›PMID 38689037›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Prevalence and risk factors of postoperative laryngeal edema in patients undergoing neck dissection.

Joo Hyun Park, Goeun Park, Kyu Hyeon Hwang, Hee Chun Cho, Junyoung Kim, Subi Oh, Han-Sin Jeong

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Joo Hyun ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-7886-1917
Goeun ParkBiomedical Statistics Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-6670-5500
Kyu Hyeon HwangDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.ORCID http://orcid.org/0009-0008-5750-8100
Hee Chun ChoDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.ORCID http://orcid.org/0009-0005-8075-3196
Junyoung KimDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-5954-733X
Subi OhDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.ORCID http://orcid.org/0009-0008-3016-6294
Han-Sin JeongDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea. hansin.jeong@samsung.com.ORCID http://orcid.org/0000-0003-4652-0573

Funding

Samsung Biomedical Research Institute OTX0001031
6 · The paper itself

Abstract

purposePostoperative laryngeal edema (PLE) is a common complication in patients undergoing head and neck surgery, leading to symptoms such as odynophagia, dysphagia, or potential airway obstruction. However, the prevalence and risk factors of PLE in patients undergoing neck dissection (ND) have not been well investigated.

methodsA retrospective analysis was conducted in three steps. Initially, a pilot study of 50 consecutive ND patients revealed a preliminary PLE prevalence of 0.34. Then, the medical records of an additional 295 ND patients were reviewed to estimate the prevalence of PLE with a total width of 95% confidence interval (CI) of ± 5%. Finally, multivariable logistic regression analyses were performed to identify risk factors for PLE (n = 343).

resultsPLE occurred in 29.4% [95%CI 24.4-34.4%] of patients undergoing any type of ND, with the most common symptoms of odynophagia (75.0%) and dyspnea (11.1%). Hospital stay was just one day longer in PLE patients, responding well with short-term steroid treatment (p = 0.0057). In multivariable analyses, no significant association was found between PLE occurrence and airway management. However, body mass index and the American Society of Anesthesiologists classification correlated with PLE. More importantly, surgery for oro-hypopharynx or supraglottis tumors (odds ratio, OR = 3.019, [95%CI 1.166-7.815]) and lymph node level 2(3) ND (OR = 4.214 to 5.279, [95%CI 1.160-20.529]) were significant risk factors for PLE.

conclusionsPLE developed in approximately 30% of ND patients, causing uncomfortable symptoms. Early diagnosis and intervention of PLE in high-risk patients can improve patient care and outcomes.

Indexed as

Laryngeal EdemaNeck DissectionPostoperative ComplicationsAdultAgedFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedPilot ProjectsPrevalenceRetrospective StudiesRisk FactorsLaryngeal edemaNeck dissectionPrevalenceRisk factors

Identifiers

PMID38689037

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.