ArticleScientific reports2024
Microwave-assisted synthesis, characterization and in vitro biomedical applications of Hibiscus rosa-sinensis Linn.-mediated carbon quantum dots.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 56 citations in OpenAlex.
- N-Doped Carbon Quantum Dots From Bauhinia purpurea With Anti-Inflammatory and Wound-Healing Properties.Chemistry & biodiversity · 2026Article
- Green Synthesis of Graphene Quantum Dots (GQDs) and Carbon Dots (CDs) Mediated with Erythrina caffra for Potential Antiviral Properties Against SARS-CoV-2.Materials (Basel, Switzerland) · 2026Article
- Carbon Dot-Based Electrochemical and Optical Sensors for Pharmaceutical Analysis and Point-of-Care Diagnostics.Biosensors · 2026Review
- Understanding the Toxicity of Carbon Dots: The Role of Synthesis Variability, Surface Chemistry, and Biological Context.International journal of molecular sciences · 2026Review
- Carbon Quantum Dots as Versatile Nanosystems for Biomedical Innovation: Mechanisms, Applications, and Translational Prospects.British journal of biomedical science · 2026Review
- Recent progress in biowaste-derived carbon dots for cancer theranostics toward a green solution to toxic metal quantum dots.Discover nano · 2025Review
- Design of a Facile Fluorescent Nano-Sensor Using Nitrogen and Sulfur Dual Doped Carbon Quantum Dots for Carbendazim Detection: A Turn-Off-On Approach for Food Safety and Environmental Monitoring.Journal of fluorescence · 2025Article
- Bio-assessments of the antibiofilm, antioxidant, and plasmid inhibitory effects of zinc selenide nanoparticles synthesized using Stachys lavandulifolia extract.Scientific reports · 2025Article
- Synthesis of carbon quantum dots based on hemp leaves and cysteamine for latent fingerprint detection and their potential therapeutic anticancer application.Nanoscale advances · 2025Article
- Dead Cell Discrimination with Red Emissive Carbon Quantum Dots from the Medicinal and Edible Herb Echinophora tenuifolia.Journal of fluorescence · 2025Article
- An Insight Into Unveiling Nano Luminescence for Industrial Dye Detection.Journal of fluorescence · 2025Article
- Therapeutic evaluation of Martynia annua derived carbon dots in epileptic Drosophila model.Scientific reports · 2025Article
- Research progress on the preparation, performance, mechanisms, and applications of carbon nanomaterials against Gram-negative bacteria.RSC advances · 2025Review
- In vitro antimicrobial and anticancer potentials of green synthesized luminescent carbon quantum dots derived from artichoke leaves.Scientific reports · 2025Article
- Dual Roles of Carbon Quantum Dots from Green Carbon Sources: A Fluorescence Sensor for FeNanomaterials (Basel, Switzerland) · 2025Article
- Microwave-assisted synthesis of biomass-derived N-doped carbon dots for metal ion sensing.Carbon research · 2025Article
- l-Cysteine-Modified Carbon Dots Derived fromACS omega · 2024Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, carbon quantum dots (CQDs) have garnered considerable attention as a promising material for biomedical applications because of their unique optical and biological properties. In this study, CQDs were derived from the leaves of Hibiscus rosa-sinensis Linn. via microwave-assisted technique and characterized using different techniques such as ultraviolet-visible, Fourier transform infrared, fluorescence spectrometry, X-ray diffraction, dynamic light scattering, transmission electron microscopy and energy-dispersive X-ray spectroscopy. Subsequently, their potential for biomedical applications was investigated through in vitro assays assessing scratch healing, anti-inflammatory, antibacterial, and cytotoxicity properties. It was found that the CQDs were fluorescent, polycrystalline, quasi-spherical, ~ 12 nm in size with presence of -OH and -COOH groups on their negatively charged surfaces, and demonstrated good anti-inflammatory by inhibiting protein denaturation, cyclooxygenase-2 and regulating inflammatory cytokines. The CQDs also exhibited antimicrobial activity against Klebsiella pneumoniae and Bacillus cereus, good biocompatibility, along with excellent promotion of cell proliferation in vitro, indicating their potential as a anti-inflammatory and wound healing material. The properties were more enhanced than their precursor, H. rosa-sinensis leaf extract. Hence, the CQDs synthesized from the leaves of H. rosa-sinensis can serve as a potential biomedical agent.
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