ArticleNature genetics2024
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.
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Article in Nature genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers, 6 of them syntheses that pooled it.
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129citing papers in PubMed, 6 pooled it
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
129 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Accelerated epigenetic age in hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Pooled it
- Associations Between Polygenic Risk Score for Blood Pressure and Risk of Hypertension in Northeast Asian Individuals.Journal of the American Heart Association · 2026Pooled it
- Genome-wide association study provides insights into the genetic basis of Lewy body dementia.Molecular psychiatry · 2025Pooled it
- Multi-ancestry investigation of the genomics of erectile dysfunction.Nature communications · 2025Pooled it
- Multi-ancestry genome-wide meta-analysis with 472,819 individuals identifies 32 novel risk loci for psoriasis.Journal of translational medicine · 2025Pooled it
- Exploring the research progression and evolutionary trends of gut microbiome and hypertension: a bibliometric analysis.Frontiers in microbiology · 2025Pooled it
- Genetic Regulation of DNA Methylation and Its Mediating Role in Blood Pressure: A Genome-Wide Twin Study.MedComm · 2026Article
- Interaction between adiposity and genetic risk score on blood pressure traits in Mexican adults.Journal of human hypertension · 2026Article
- Proteome-wide genetic analyses identify ASGR1 as a potential biomarker linking smoking with ischemic heart disease.Nature cardiovascular research · 2026Article
- Irritable Bowel Syndrome and Incident Hypertension: Epidemiologic and Genetic Insights.Biomedicines · 2026Article
- Article
- Genetic determinants of childhood blood pressure and heart rate in relation to adult health outcomes: the consortium of childhood blood pressure.European heart journal · 2026Article
- Article
- Unveiling the Immune Mechanisms of Hypertension With Single-Cell Transcriptome-Wide Mendelian Randomization.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- SNPannotator: automated functional annotation of genetic variants and linked proxies.Bioinformatics (Oxford, England) · 2026Article
- Partitioned blood pressure polygenic risk reveals differential genetic effects of tissue-specific enhancers and their interactions on cardiovascular disease.Research square · 2026Article
- Comparing genome-wide significant and chemosensory variants as instruments for dietary patterns in Mendelian randomization.International journal of epidemiology · 2026Article
- Transcriptome profiling of human hypothalamic agouti-related protein and proopiomelanocortin neurons regulating energy homeostasis.Nature communications · 2026Article
- Importance of Hypercortisolism in BP Control, Cardiovascular Risk and in Patients With Difficult-to-Control Hypertension: An Overview for Primary Care Physicians.Diabetes, obesity & metabolism · 2026Review
- Deep learning prediction of left atrial structure and function from 12-lead electrocardiograms.Nature communications · 2026Article
69 more citing papers are in PubMed but not listed here.
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Authors and funding
151 authors.
Jacob M Keaton *Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Zoha Kamali *Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0001-6492-5887
Tian Xie *Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0003-2442-7941
Ahmad VaezDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. a.vaez@umcg.nl.ORCID http://orcid.org/0000-0001-9048-3795
Ariel WilliamsCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Slavina B GolevaCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-5177-9286
Alireza AniDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0002-7868-3118
Evangelos EvangelouDepartment of Epidemiology and Biostatistics, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-5488-2999
Jacklyn N HellwegeDivision of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID http://orcid.org/0000-0001-7479-0920
Loic YengoInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
William J YoungClinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0002-9831-6817
Matthew TraylorClinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Ayush GiriDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Zhili ZhengInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0003-2102-221X
Jian ZengInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
Daniel I ChasmanDivision of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA.
Andrew P MorrisCentre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0002-6805-6014
Mark J CaulfieldClinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0001-9295-3594
Shih-Jen HwangPopulation Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.
Jaspal S KoonerNational Heart and Lung Institute, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-2086-4837
David ConenPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
John R AttiaFaculty of Health and Medicine, University of Newcastle, New Lambton Heights, Newcastle, New South Wales, Australia.ORCID http://orcid.org/0000-0001-9800-1308
Alanna C MorrisonHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID http://orcid.org/0000-0001-6381-4296
Ruth J F LoosThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-8532-5087
Kati KristianssonDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
Reinhold SchmidtDepartment of Neurology/Medical University Graz, Graz, Austria.
Andrew A HicksInstitute for Biomedicine, Eurac Research, Bolzano, Italy.ORCID http://orcid.org/0000-0001-6320-0411
Peter P PramstallerInstitute for Biomedicine, Eurac Research, Bolzano, Italy.ORCID http://orcid.org/0000-0002-9831-8302
Christopher P NelsonDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Nilesh J SamaniDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Lorenz RischFaculty of Medical Sciences, Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.ORCID http://orcid.org/0000-0003-2692-6699
Ulf GyllenstenImmunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-6316-3355
Olle MelanderDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Harriette RieseInterdisciplinary Center Psychopathology and Emotional Regulation (ICPE), Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
James F WilsonCentre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland.ORCID http://orcid.org/0000-0001-5751-9178
Harry CampbellCentre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland.
Stephen S RichCenter for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.ORCID http://orcid.org/0000-0003-3872-7793
Bruce M PsatyCardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Systems and Population Health, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-7278-2190
Yingchang LuVanderbilt Genetic Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Jerome I RotterThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID http://orcid.org/0000-0001-7191-1723
Xiuqing GuoThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID http://orcid.org/0000-0002-5264-5068
Kenneth M RiceDepartment of Biostatistics, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3071-7278
Peter VollenweiderDepartment of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Johan SundströmDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.
Claudia LangenbergMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-5017-7344
Martin D TobinDepartment of Health Sciences, University of Leicester, Leicester, UK.ORCID http://orcid.org/0000-0002-3596-7874
Vilmantas GiedraitisDepartment of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0003-3423-2021
Jian'an LuanMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-3137-6337
Jaakko TuomilehtoDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
Zoltan KutalikCenter for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
Samuli RipattiInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0002-0504-1202
Veikko SalomaaDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.ORCID http://orcid.org/0000-0001-7563-5324
Giorgia GirottoDepartment of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.ORCID http://orcid.org/0000-0003-4507-6589
Stella TrompetDepartment Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.ORCID http://orcid.org/0000-0001-5006-0528
J Wouter JukemaDepartment of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
Pim van der HarstDepartment of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands.
Paul M RidkerDivision of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA.
Franco GiulianiniDivision of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA.
Veronique VitartMRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.ORCID http://orcid.org/0000-0002-4991-3797
Anuj GoelWellcome Centre for Human Genetics, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-2307-4021
Hugh WatkinsWellcome Centre for Human Genetics, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-5287-9016
Sarah E HarrisLothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-4941-5106
Ian J DearyLothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-1733-263X
Peter J van der MostDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0001-8450-3518
Albertine J OldehinkelDepartment of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0003-3925-3913
Bernard D KeavneyDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0001-9573-0812
Caroline HaywardMRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.ORCID http://orcid.org/0000-0002-9405-9550
Archie CampbellCentre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-0198-5078
Michael BoehnkeDepartment of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-6442-7754
Laura J ScottDepartment of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-4886-5084
Thibaud BoutinMRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.ORCID http://orcid.org/0000-0003-4754-1675
Chrysovalanto MamasoulaPopulation Health Sciences Institute, Newcastle University, Newcastle, UK.
Marjo-Riitta JärvelinDepartment of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Annette PetersInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.ORCID http://orcid.org/0000-0001-6645-0985
Christian GiegerResearch Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.ORCID http://orcid.org/0000-0001-6986-9554
Edward G LakattaLaboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-4772-0035
Francesco CuccaInstitute of Genetic and Biomedical Research, National Research Council (CNR), Monserrato, Italy.ORCID http://orcid.org/0000-0002-7414-1995
Jennie HuiBusselton Population Medical Research Institute, Perth, Western Australia, Australia.
Paul KnektPopulation Health Unit, Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
Stefan EnrothDepartment of Immunology, Genetics, and Pathology, Biomedical Center, Science for Life Laboratory (SciLifeLab) Uppsala, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-5056-9137
Martin H De BorstDepartment of Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0002-4127-8733
Ozren PolašekUniversity of Split School of Medicine, Split, Croatia.
Maria Pina ConcasInstitute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy.
Eulalia CatamoInstitute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy.ORCID http://orcid.org/0000-0002-4701-9134
Massimiliano CoccaInstitute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy.ORCID http://orcid.org/0000-0002-1127-7596
Ruifang Li-GaoDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Edith HoferClinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.
Helena SchmidtGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0001-9773-9992
Beatrice SpedicatiDepartment of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.ORCID http://orcid.org/0000-0002-7432-4708
Melanie WaldenbergerResearch Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.ORCID http://orcid.org/0000-0003-0583-5093
David P StrachanPopulation Health Sciences Institute St George's, University of London, London, UK.
Maris LaanInstitute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.ORCID http://orcid.org/0000-0002-8519-243X
Alexander TeumerInstitute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0002-8309-094X
Marcus DörrDZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.
Vilmundur GudnasonIcelandic Heart Association, Kopavogur, Iceland.ORCID http://orcid.org/0000-0001-5696-0084
James P CookDepartment of Health Data Science, University of Liverpool, Liverpool, UK.
Daniela RuggieroIRCCS Neuromed, Pozzilli, Italy.ORCID http://orcid.org/0000-0003-3898-7827
Ivana KolcicAlgebra University College, Zagreb, Croatia.ORCID http://orcid.org/0000-0001-7918-6052
Eric BoerwinkleHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Michela TragliaDivision of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
Olli T RaitakariCentre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.
Andrew D JohnsonPopulation Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.ORCID http://orcid.org/0000-0001-6369-5178
Christopher Newton-ChehMedical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-3001-9111
Morris J BrownClinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0001-8409-1082
Anna F DominiczakInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0003-4913-3608
Peter J SeverInternational Centre for Circulatory Health, Imperial College London, London, UK.
Neil PoulterSchool of Public Health, Imperial College London, London, UK.
John C ChambersLee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0003-0209-4541
Roberto ElosuaHospital del Mar Research Institute (IMIM), Barcelona, Spain.
David SiscovickNew York Academy of Medicine, New York, NY, USA.
Tõnu EskoInstitute of Genomics, University of Tartu, Tartu, Estonia.
Andres MetspaluInstitute of Genomics, University of Tartu, Tartu, Estonia.ORCID http://orcid.org/0000-0002-3718-796X
Rona J StrawbridgeInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0001-8506-3585
Markku LaaksoInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0002-3394-7749
Anders HamstenDivision of Cardiovascular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Jouke-Jan HottengaDepartment of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-5668-2368
Eco de GeusDepartment of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands.
Andrew D MorrisData Science, University of Edinburgh, Edinburgh, UK.
Colin N A PalmerPopulation Health and Genomics, School of Medicine, University of Dundee, Dundee, UK.ORCID http://orcid.org/0000-0002-6415-6560
Ilja M NolteDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0001-5047-4077
Yuri MilaneschiAmsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-3697-6617
Jonathan MartenCentre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK.
Alan WrightCentre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK.
Eleftheria ZegginiInstitute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.ORCID http://orcid.org/0000-0003-4238-659X
Joanna M M HowsonDepartment of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-7618-0050
Christopher J O'DonnellVA Boston Healthcare System, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Tim SpectorDepartment of Twin Research, King's College London, London, UK.ORCID http://orcid.org/0000-0002-9795-0365
Mike A NallsCenter for Alzheimer's and Related Dementias, NIA/NINDS, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-0319-4325
Eleanor M SimonsickIntramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Yongmei LiuDivision of Cardiology, Duke University School of Medicine, Durham, NC, USA.
Cornelia M van DuijnNuffield Department of Population Health, Big Data Institute, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-2374-9204
Adam S ButterworthBritish Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-6915-9015
John N DaneshBritish Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Cristina MenniDepartment of Twin Research and Genetic Epidemiology, London, UK.ORCID http://orcid.org/0000-0001-9790-0571
Nicholas J WarehamMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-1422-2993
Kay-Tee KhawDepartment of Public Health and Primary Care, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Yan V SunDepartment of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia, USA.ORCID http://orcid.org/0000-0002-2838-1824
Peter W F WilsonEmory Clinical Cardiovascular Research Institute, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-5653-7056
Kelly ChoDivision of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Peter M VisscherInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-2143-8760
Joshua C DennyCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-3049-7332
Million Veteran Program
Lifelines Cohort Study
CHARGE consortium
ICBP Consortium
Daniel LevyPopulation Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.
Todd L EdwardsDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. todd.l.edwards@vumc.org.ORCID http://orcid.org/0000-0003-4318-6119
Patricia B MunroeClinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0002-4176-2947
Harold SniederDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0003-1949-2298
Helen R WarrenClinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. h.r.warren@qmul.ac.uk.ORCID http://orcid.org/0000-0003-0511-1386
Funding
CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5MIdentifying Genes for Type 2 Diabetes:FUSIONR01DK062370 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOEHNKE, MICHAEL L, SCOTT, LAURA J. · 2003 to 2025
$6.7MImproving precision health approaches through large-scale EHRs and biobanksZIAHG200417 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI DENNY, JOSHUA · 2022 to 2024
$4.2MGenome-wide Association Study of Cardiovascular Traits in 6142 SardiniansZIAAG000799 · NIA · NATIONAL INSTITUTE ON AGING · PI LAKATTA, EDWARD · 2009 to 2025
$1.8MCardiovascular Disease Risk Factors, Cardiovascular Disease Risk Prediction, and Genetics in the Million Veteran ProgramI01BX004821 · VA · VETERANS HEALTH ADMINISTRATION · PI PETER WYMAN WILSON · 2020 to 2026
–BLRD VA I01 BX004821NIDDK NIH HHS R01 DK062370
Abstract
Hypertension affects more than one billion people worldwide. Here we identify 113 novel loci, reporting a total of 2,103 independent genetic signals (P < 5 × 10
Indexed as
Blood PressureGenetic Predisposition to DiseaseGenome-Wide Association StudyHypertensionMultifactorial InheritancePolymorphism, Single NucleotideFemaleGenetic Risk ScoreHumansMaleRisk Factors
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