Evidence map›Paper›PMID 38688636›Full record

ArticleIn vivo (Athens, Greece)

Membranous Nephropathy as a Paraneoplastic Syndrome in Cancer of Unknown Primary.

Kyoichi Kaira, Hiroaki Amano, Hisao Imai, Hirokazu Okada, Hiroshi Kagamu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyoichi KairaDepartment of Respiratory Medicine, Comprehensive Cancer Center, International Medical Center, Hidaka, Japan; kkaira1970@yahoo.co.jp.
Hiroaki AmanoDepartment of Nephrology, Faculty of Medicine, Saitama Medical University, Moroyama, Japan.
Hisao ImaiDepartment of Respiratory Medicine, Comprehensive Cancer Center, International Medical Center, Hidaka, Japan.
Hirokazu OkadaDepartment of Nephrology, Faculty of Medicine, Saitama Medical University, Moroyama, Japan.
Hiroshi KagamuDepartment of Respiratory Medicine, Comprehensive Cancer Center, International Medical Center, Hidaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimMembranous nephropathy (MN) is a nephrotic syndrome with both idiopathic and secondary etiologies. The mechanism of cancer-associated MN is presumed to involve the immunological production of antibodies against a tumor antigen, although little is known about the detailed mechanism. Lung cancer is a major neoplasm associated with cancer-associated MN. However, the simultaneous occurrence of secondary MN in patients with cancer of unknown primary (CUP) remains unclear. CASE REPORT: Here, we present a case of secondary MN in a 72-year-old female as a paraneoplastic syndrome in CUP. Thoracic radiotherapy up to a total of 60 Gy was initially performed on the right subclavian and mediastinal lymph nodes. Computed tomography revealed marked shrinking of these lymph nodes, and the secondary MN also improved without any symptoms.

conclusionThe presence of proteinuria in patients with CUP suggests the possibility of secondary MN as a rare differential diagnosis.

Indexed as

Glomerulonephritis, MembranousNeoplasms, Unknown PrimaryParaneoplastic SyndromesAgedDiagnosis, DifferentialFemaleHumansTomography, X-Ray Computedcancer of unknown primaryMembranous nephropathyparaneoplasticradiotherapy

Identifiers

PMID38688636
PMCPMC11059915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.