Evidence map›Paper›PMID 38687902›Full record

ArticleJournal of natural products2024

Chemical Transformation of B- to A-type Proanthocyanidins and 3D Structural Implications.

Shu-Xi Jing, Connor M McDermott, Parker L Flanders, Mariana Reis-Havlat, Shao-Nong Chen, Ana K Bedran-Russo, James B McAlpine, Elizabeth A Ambrose, Guido F Pauli

Abstract read
In one paragraph

Article in Journal of natural products, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Current approaches to produce durable biomaterials: Trends in polymeric materials for restorative dentistry applications.Dental materials : official publication of the Academy of Dental Materials · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Connor M McDermottDepartment of Chemistry, Grandview University, Des Moines, Iowa 50316, United States.ORCID 0000-0001-5167-1849
Parker L Flanders
Mariana Reis-HavlatORCID 0000-0002-0865-4311
Ana K Bedran-RussoORCID 0000-0002-3670-9519
Elizabeth A AmbroseORCID 0000-0003-4275-3513

Funding

Dentin Biomodification for Optimization of Bioadhesive Dental RestorationsR01DE028194 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BEDRAN-RUSSO, ANA KARINA B · 2019 to 2023
$2.6M
NIDCR NIH HHS R01 DE028194
6 · The paper itself

Abstract

In nature, proanthocyanidins (PACs) with A-type linkages are relatively rare, likely due to biosynthetic constraints in the formation of additional ether bonds to be introduced into the more common B-type precursors. However, A-type linkages confer greater structural rigidity on PACs than do B-type linkages. Prior investigations into the structure-activity relationships (SAR) describing how plant-derived PACs with B- and complex AB-type linkages affect their capacity for dentin biomodification indicate that a higher ratio of double linkages leads to a greater interaction with dentin type I collagen. Thus, A-type PACs emerge as particularly intriguing candidates for interventional functional biomaterials. This study employed a free-radical-mediated oxidation using DPPH to transform trimeric and tetrameric B-type PACs,

Indexed as

ProanthocyanidinsMolecular StructureStructure-Activity RelationshipProanthocyanidins

Identifiers

PMID38687902
PMCPMC11732641

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.