ArticleProceedings of the National Academy of Sciences of the United States of America2024
Voltage-induced calcium release in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- METTL3-mediated mMolecular cancer · 2026Article
- Advances in drug addiction research usingFrontiers in cell and developmental biology · 2026Review
- Mechanosensitive channel Piezo1 in calcium dynamics: structure, function, and emerging therapeutic strategies.Frontiers in molecular biosciences · 2025Review
- Response to Allard: A minor (albeit significant) role for voltage-induced calcium release inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Early characterization of excitation-contraction coupling and SLO-2 channel properties inProceedings of the National Academy of Sciences of the United States of America · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Type 1 voltage-activated calcium channels (CaV1) in the plasma membrane trigger calcium release from the sarcoplasmic reticulum (SR) by two mechanisms. In voltage-induced calcium release (VICR), CaV1 voltage sensing domains are directly coupled to ryanodine receptors (RYRs), an SR calcium channel. In calcium-induced calcium release (CICR), calcium ions flowing through activated CaV1 channels bind and activate RYR channels. VICR is thought to occur exclusively in vertebrate skeletal muscle while CICR occurs in all other muscles (including all invertebrate muscles). Here, we use calcium-activated SLO-2 potassium channels to analyze CaV1-SR coupling in
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Registered trials
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