Evidence map›Paper›PMID 38687725›Full record

ArticlePloS one2024

Asymptomatic hypoglycemia among preterm newborns: A cross-sectional analysis.

Shani S Salum, Florence S Kalabamu, Maulidi R Fataki, Salha A Omary, Ummulkheir H Mohammed, Hillary A Kizwi, Kelvin M Leshabari

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Shani S SalumDept of Paediatrics/Child Health, Hubert Kairuki Memorial University, Dar es Salaam, Tanzania.
Florence S KalabamuDept of Paediatrics/Child Health, Hubert Kairuki Memorial University, Dar es Salaam, Tanzania.
Maulidi R FatakiDept of Paediatrics/Child Health, Hubert Kairuki Memorial University, Dar es Salaam, Tanzania.
Salha A OmaryDept of Paediatrics/Child Health, Hubert Kairuki Memorial University, Dar es Salaam, Tanzania.
Ummulkheir H MohammedDept of Paediatrics/Child Health, Hubert Kairuki Memorial University, Dar es Salaam, Tanzania.
Hillary A KizwiDept of Obstetrics/Gynaecology, Muhimbili National Hospital (Mloganzila), Dar es Salaam, Tanzania.
Kelvin M LeshabariAgeing Initiative in Sub-Saharan Africa (AISA) Research Group, Registered Trustees of Ultimate Family Healthcare, Dar es Salaam, Tanzania.ORCID 0000-0003-2663-993X
Aga Khan University · TZHubert Kairuki Memorial University · TZDar es Salaam Institute of Technology · TZMuhimbili National Hospital · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypoglycemia is the commonest metabolic abnormality encountered in newborns. Besides, there is a growing body of evidence that links the causes of early neonatal mortality to neonatal hypoglycemia in Tanzania. However exact factors associated with asymptomatic hypoglycemia in preterm newborns are not known.

objectiveTo assess factors associated with asymptomatic hypoglycemia among preterm newborns. MATERIALS AND

methodsA cross sectional, analytical hospital- based study was carried out at Dar es salaam public regional referral hospitals. Preterm newborns with asymptomatic hypoglycemia were the target population. Data on demographic and clinical characteristics of preterm newborns and their mothers were collected and analyzed using Epi-Info™ software version 7.4. Main data analysis was done by applying a multivariable binary logistic regression model with neonatal random glycaemia coded in a binary fashion at a cut-off point of 2.6 mmol/L. An α-level of 5% was used as a limit of type I error.

resultsWe recruited and analysed 217 preterm newborns within 6-24 hours post-delivery. Male: Female = 1.1:1 (females n = 105, 48.4%). Median glycemic level was 2.6 (IQR; 2.1-3.9) mmol/L. Median gestational age at delivery was 33 (IQR: 30-35) weeks. Breastfeeding within 1st hour post-delivery was a statistically significant factor against glycemic levels associated with hypoglycemia (OR; 0.123, 95%-CI; 0.052-0.287) in a fitted multivariable logistic regression model.

conclusionAbout half of all preterm newborns studied had glycemic values in a statistical range associated with hypoglycemia. Exclusive breast feeding within 1st hour post-delivery was associated with glycemic levels protective from risk of asymptomatic neonatal hypoglycemia. RECOMMENDATIONS: Exclusive breastfeeding practices within 1st hour post-delivery may need to be emphasized to all expectant mothers in order to avoid potential risk of asymptomatic hypoglycemia in preterm newborns.

Indexed as

HypoglycemiaInfant, PrematureAdultBlood GlucoseBreast FeedingCross-Sectional StudiesFemaleGestational AgeHumansInfant, NewbornLogistic ModelsMaleRisk FactorsTanzaniaBlood Glucose

Identifiers

PMID38687725
PMCPMC11060517
OpenAlexW4396531680

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.