Evidence map›Paper›PMID 38687362›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Changes in interhemispheric coherence after total corpus callosotomy: a scalp EEG study in children with non-lesional generalized epilepsy.

Vich Yindeedej, Takehiro Uda, Shugo Nishijima, Takeshi Inoue, Ichiro Kuki, Masataka Fukuoka, Megumi Nukui, Shin Okazaki, Noritsugu Kunihiro, Ryoko Umaba and 1 more

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3 citing papers in PubMed.

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5 · Who and what money

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11 authors.

Vich YindeedejDepartment of Neurosurgery, Osaka Metropolitan University, Graduate School of Medicine, Osaka, Japan.
Takehiro UdaDepartment of Neurosurgery, Osaka Metropolitan University, Graduate School of Medicine, Osaka, Japan. udat@omu.ac.jp.
Shugo NishijimaDepartment of Neurosurgery, Osaka Metropolitan University, Graduate School of Medicine, Osaka, Japan.
Takeshi InoueDepartment of Pediatric Neurology, Osaka City General Hospital, Osaka, Japan.
Ichiro KukiDepartment of Pediatric Neurology, Osaka City General Hospital, Osaka, Japan.
Masataka FukuokaDepartment of Pediatric Neurology, Osaka City General Hospital, Osaka, Japan.
Megumi NukuiDepartment of Pediatric Neurology, Osaka City General Hospital, Osaka, Japan.
Shin OkazakiDepartment of Pediatric Neurology, Osaka City General Hospital, Osaka, Japan.
Noritsugu KunihiroDepartment of Pediatric Neurosurgery, Osaka City General Hospital, Osaka, Japan.
Ryoko UmabaDepartment of Pediatric Neurosurgery, Osaka City General Hospital, Osaka, Japan.
Takeo GotoDepartment of Neurosurgery, Osaka Metropolitan University, Graduate School of Medicine, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCoherence analysis in electroencephalography (EEG) allows measurement of the degree of consistency of amplitude between pairs of electrodes. Theoretically, disconnective epilepsy surgery should decrease coherence between corresponding areas. The study aimed to evaluate postoperative changes in interhemispheric coherence values after corpus callosotomy (CC).

methodsNon-lesional, drug-resistant, generalized epilepsy patients who underwent total CC were retrospectively collected. To evaluate coherence, we divided the scalp interictal EEG into "baseline" and "discharge" states after excluding periods with artifacts. Interhemispheric coherence values were obtained between eight pairs of symmetrically opposite scalp electrodes in six different frequency bands. We analyzed both pre- and postoperative EEG sessions and calculated the percentage of difference (POD) in coherence values.

resultsWe collected 13 patients and analyzed 2496 interhemispheric coherence values. Preoperative coherence values differed significantly between baseline and discharge states (p = 0.0003), but postoperative values did not (p = 0.11). For baseline state, coherence values were decreased after CC and median POD was - 22.3% (p < 0.0001). Delta frequency showed the most decreased POD (-44.3%, p = 0.0009). Median POD was lowest in the Fp1-Fp2 pair of electrodes. For discharge state, coherence values were decreased after CC and median POD was - 24.7% (p < 0.0001). Delta frequency again showed the most decreased POD (-55.9%, p = 0.0016). Median POD was lowest in the F7-F8 pair.

conclusionAfter total CC, interhemispheric coherence decreased significantly in both baseline and discharge states. The most decreased frequency band was the delta band, which may be used as a representative frequency band in future studies.

Indexed as

Corpus CallosumElectroencephalographyEpilepsy, GeneralizedScalpAdolescentChildChild, PreschoolDrug Resistant EpilepsyFemaleHumansMaleRetrospective StudiesCoherenceEpilepsyInterhemispheric coherenceScalp EEGTotal corpus callosotomy

Identifiers

PMID38687362

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.