Evidence map›Paper›PMID 38687069›Full record

Trial reportMicrobiology spectrum2024

Effect of probiotic administration during pregnancy on the functional diversity of the gut microbiota in healthy pregnant women.

Guangyu Ma, Hao Yan, Kian Deng Tye, Xiaomei Tang, Huijuan Luo, Zhe Li, Xiaomin Xiao

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guangyu Ma *Department of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.ORCID 0009-0004-4801-9824
Hao Yan *Department of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Kian Deng TyeDepartment of Obstetrics and Gynecology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiaomei TangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Huijuan LuoDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Zhe LiDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.ORCID 0009-0009-3725-2248
Xiaomin XiaoDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China.ORCID 0009-0007-2810-2294

Funding

Guangdong Provincial Key Laboratory of Human Digital Twin 2022B1212010004National Natural Science Foundation of China-China Academy of General Technology Joint Fund for Basic Research 81771664
6 · The paper itself

Abstract

Our study aims to investigate the impact of probiotic consumption during pregnancy on gut microbiota functional diversity in healthy pregnant women. Thirty-two pregnant women were randomly assigned to two groups. The probiotic group (PG) consisted of pregnant women who consumed triple viable IMPORTANCE: Probiotics are considered beneficial to human health. There is limited understanding of how probiotic consumption during pregnancy affects the functional diversity of the gut microbiota. The aim of our study is to investigate the impact of probiotic consumption during pregnancy on the functional diversity of the gut microbiota. Our findings suggest that probiotic supplementation during pregnancy has a significant impact on functional metabolism. This could potentially open up new avenues for preventing various pregnancy-related complications. This also provides new insights into the effects of probiotic consumption during pregnancy on the gut microbiota and offers a convenient method for exploring the potential mechanisms underlying the impact of probiotics on the gut microbiota of pregnant women.

Indexed as

Gastrointestinal MicrobiomeProbioticsRNA, Ribosomal, 16SAdultBacteriaBifidobacterium longumFecesFemaleHumansLactobacillus delbrueckiiPregnancyStreptococcus thermophilusYoung AdultRNA, Ribosomal, 16Sfunctional predictiongut microbiotapredictive metagenome profilingpregnancyprobiotic

Identifiers

PMID38687069
PMCPMC11237737

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.