Evidence map›Paper›PMID 38686684›Full record

Observational studyTexas Heart Institute journal2024

Three-Year Clinical Outcomes With the Cilotax Dual Drug-Eluting Stent vs Everolimus-Eluting Stents in Patients With Acute Myocardial Infarction.

HyeYon Yu, Jihun Ahn, Byoung Geol Choi, Soohyung Park, Dong Oh Kang, Cheol Ung Choi, Seung-Woon Rha, Myung Ho Jeong

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Texas Heart Institute journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

HyeYon YuSchool of Nursing, College of Medicine, Soonchunhyang University, Asan, Republic of Korea.
Jihun AhnDepartment of Internal Medicine, Daejeon Eulji Medical Center, Eulji University College of Medicine, Daejeon, Republic of Korea.
Byoung Geol ChoiCardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
Soohyung ParkCardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
Dong Oh KangCardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
Cheol Ung ChoiCardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
Seung-Woon RhaCardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
Myung Ho JeongDivision of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study compared the safety and effectiveness of paclitaxel/cilostazol-eluting Cilotax stents with those of everolimus-eluting stents in patients with acute myocardial infarction. Real-world data from the Korea Acute Myocardial Infarction Registry were examined.

methodsA total of 5,472 patients with acute myocardial infarction underwent percutaneous coronary intervention with Cilotax stents (n = 212) or everolimus-eluting stents (n = 5,260). The primary end point was the 3-year rate of target lesion failure. The other end points were major adverse cardiovascular events (a composite of cardiac death, target vessel myocardial infarction, and ischemia-driven target lesion revascularization), target vessel revascularization, and stent thrombosis. A propensity score matching analysis was performed to adjust for potential confounders by using a logistic regression model; propensity score matching generated 2 well-balanced groups (Cilotax group, n = 180; everolimus-eluting stents group, n = 170; N = 350). After propensity score matching, baseline clinical characteristics were similar between the groups.

resultsAfter percutaneous coronary intervention, compared with the everolimus-eluting stents group, the Cilotax group more often had major adverse cardiovascular events (24.1% vs 18.5%; P = .042), myocardial infarction (8.0% vs 3.2%; P < .001), target lesion revascularization (8.0% vs 2.6%; P < .001), target vessel revascularization (11.3% vs 4.5%; P < .001), and stent thrombosis (4.7% vs 0.5%; P < .001) before matching. Even after matching, the Cilotax group had more frequent target lesion revascularization (9.4% vs 2.9%; P = .22) and stent thrombosis (5.6% vs 1.2%; P = .34).

conclusionIn patients with acute myocardial infarction who underwent percutaneous coronary intervention, use of the Cilotax stent was associated with higher rates of target lesion revascularization, target vessel revascularization, and stent thrombosis than were everolimus-eluting stents. Use of the Cilotax dual drugeluting stent should be avoided in the treatment of myocardial infarction.

Indexed as

Drug-Eluting StentsEverolimusMyocardial InfarctionPercutaneous Coronary InterventionProsthesis DesignRegistriesAgedFemaleFollow-Up StudiesHumansImmunosuppressive AgentsMaleMiddle AgedPropensity ScoreRepublic of KoreaRetrospective StudiesEverolimusImmunosuppressive Agentsdrug-eluting stentsMyocardial infarctionpercutaneous coronary intervention

Identifiers

PMID38686684
PMCPMC11075153

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.