Evidence map›Paper›PMID 38686660›Full record

ReviewThe Australian & New Zealand journal of obstetrics & gynaecology2024

Why does hormonal contraception and menopausal hormonal treatment have such a small effect on breast cancer risk?

John A Eden

Abstract readReview
In one paragraph

Review in The Australian & New Zealand journal of obstetrics & gynaecology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

John A EdenRoyal Hospital for Women, University of NSW, Sydney, New South Wales, Australia.ORCID 0009-0000-8671-268X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oestrogen is considered by many to be a major cause of breast cancer, and yet hormonal contraception and menopausal hormonal therapy have a paradoxically small effect on breast cancer risk. Also, in the oestrogen-only arm of the Women's Health Initiative, subjects given oestrogen had a reduced risk of breast cancer compared to controls. Initiation of breast cancer likely begins early in life, in the long-lived ER

Indexed as

Breast NeoplasmsEstrogen Replacement TherapyHormonal ContraceptionEstrogensFemaleHumansMenopauseProgestinsRisk FactorsEstrogensProgestinsbreast cancercausalitycontraceptionmenopausal hormone therapyrisk factor

Identifiers

PMID38686660
PMCPMC11660022

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.