Evidence map›Paper›PMID 38686579›Full record

ArticleLa Medicina del lavoro2024

Cholangiocarcinoma and Occupational Exposure to Asbestos: Insights From the Italian Pooled Cohort Study.

Stefania Curti, Mena Gallo, Daniela Ferrante, Francesca Bella, Lorenza Boschetti, Veronica Casotto, Marcello Ceppi, Daniela Cervino, Lucia Fazzo, Ugo Fedeli and 19 more

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In one paragraph

Article in La Medicina del lavoro, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

29 authors.

Stefania CurtiDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
Mena GalloDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
Daniela FerranteUnit of Medical Statistics, Department of Translational Medicine, Università del Piemonte Orientale and Cancer Epidemiology Unit, CPO-Piemonte, Novara, Italy.
Francesca BellaSyracuse Cancer Registry, Provincial Health Authority of Syracuse, Italy.
Lorenza BoschettiHealth Protection Agency of Pavia (ATS Pavia), Pavia, Italy.
Veronica CasottoEpidemiological Department, Azienda Zero, Veneto Region, Padova, Italy.
Marcello CeppiClinical Epidemiology Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Daniela CervinoDepartment of Public Health, Azienda USL di Bologna, Italy.
Lucia FazzoDepartment of Environment and Health, Istituto Superiore di Sanità, Roma, Italy.
Ugo FedeliEpidemiological Department, Azienda Zero, Veneto Region, Padova, Italy.
Paolo Giorgi RossiEpidemiology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Lucia GiovannettiInstitute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.
Paolo GirardiDepartment of Environmental Sciences, Informatics and Statistics, Ca' Foscari University of Venice, Venice, Italy.
Cecilia LandoClinical Epidemiology Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Enrica MiglioreUnit of Cancer Epidemiology, Regional Operating Center of Piemonte (COR Piemonte), University of Torino and CPO-Piemonte, Torino, Italy.
Lucia MiligiInstitute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.
Enrico OddoneDepartment of Public Health, Experimental and Forensic Medicine - University of Pavia, Pavia, Italy.
Vincenza PerlangeliDepartment of Public Health, Azienda USL di Bologna, Italy.
Roberta PernettiDepartment of Public Health, Experimental and Forensic Medicine - University of Pavia, Pavia, Italy.
Sara PiroInstitute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.
Cinzia StorchiEpidemiology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Rosario TuminoSyracuse Cancer Registry, Provincial Health Authority of Syracuse, Italy.
Amerigo ZonaDepartment of Environment and Health, Istituto Superiore di Sanità, Roma, Italy.
Manuel ZorziEpidemiological Department, Azienda Zero, Veneto Region, Padova, Italy.
Giovanni BrandiDepartment of Medical and Surgical Sciences, University of Bologna, Italy; Oncology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy.
Stefano FerrettiEmilia-Romagna Cancer Registry, Ferrara Unit, Local Health Authority, Ferrara; and University of Ferrara, Italy.
Corrado MagnaniUnit of Medical Statistics, Department of Translational Medicine, Università del Piemonte Orientale and Cancer Epidemiology Unit, CPO-Piemonte, Novara, Italy.
Alessandro MarinaccioDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority, Rome, Italy.
Stefano MattioliDepartment of Environmental and Prevention Sciences, University of Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies supported the association between occupational exposure to asbestos and risk of cholangiocarcinoma (CC). Aim of the present study is to investigate this association using an update of mortality data from the Italian pooled asbestos cohort study and to test record linkage to Cancer Registries to distinguish between hepatocellular carcinoma (HCC) and intrahepatic/extrahepatic forms of CC.

methodsThe update of a large cohort study pooling 52 Italian industrial cohorts of workers formerly exposed to asbestos was carried out. Causes of death were coded according to ICD. Linkage was carried out for those subjects who died for liver or bile duct cancer with data on histological subtype provided by Cancer Registries.

results47 cohorts took part in the study (57,227 subjects). We identified 639 causes of death for liver and bile duct cancer in the 44 cohorts covered by Cancer Registry. Of these 639, 240 cases were linked to Cancer Registry, namely 14 CC, 83 HCC, 117 cases with unspecified histology, 25 other carcinomas, and one case of cirrhosis (likely precancerous condition). Of the 14 CC, 12 occurred in 2010-2019, two in 2000-2009, and none before 2000.

conclusionFurther studies are needed to explore the association between occupational exposure to asbestos and CC. Record linkage was hampered due to incomplete coverage of the study areas and periods by Cancer Registries. The identification of CC among unspecific histology cases is fundamental to establish more effective and targeted liver cancer screening strategies.

Indexed as

AsbestosBile Duct NeoplasmsCholangiocarcinomaOccupational DiseasesOccupational ExposureAgedCarcinoma, HepatocellularCohort StudiesFemaleHumansItalyLiver NeoplasmsMaleMiddle AgedRegistriesAsbestos

Identifiers

PMID38686579
PMCPMC11181221

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