Evidence map›Paper›PMID 38686335›Full record

Articlenpj antimicrobials and resistance2024

The impact of antibiotics on the gut microbiota of children recovering from watery diarrhoea.

Son-Nam H Le, Chau Nguyen Ngoc Minh, Paola Florez de Sessions, Song Jie, Chau Tran Thi Hong, Guy E Thwaites, Stephen Baker, Duy Thanh Pham, Hao Chung The

Abstract read
In one paragraph

Article in npj antimicrobials and resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Son-Nam H LeOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.ORCID 0000-0002-8131-5885
Chau Nguyen Ngoc MinhOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Paola Florez de SessionsGenome Institute of Singapore, Singapore, Singapore.
Song JieGenome Institute of Singapore, Singapore, Singapore.
Chau Tran Thi HongOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Guy E ThwaitesOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Stephen BakerDepartment of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Diseases (CITIID), University of Cambridge, Cambridge, United Kingdom.
Duy Thanh PhamOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Hao Chung TheOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.ORCID 0000-0002-4028-4074

Funding

Wellcome Trust
6 · The paper itself

Abstract

Infectious diarrhoeal diseases remain a substantial health burden in young children in low- and middle-income countries. The disease and its variable treatment options significantly alter the gut microbiome, which may affect clinical outcomes and overall gut health. Antibiotics are often prescribed, but their impact on the gut microbiome during recovery is unclear. Here, we used 16S rRNA sequencing to investigate changes in the gut microbiota in Vietnamese children with acute watery diarrhoea, and highlight the impact of antibiotic treatment on these changes. Our analyses identified that, regardless of treatment, recovery was characterised by reductions in

Indexed as

AntibioticsGastroenteritisMicrobiome

Identifiers

PMID38686335
PMCPMC11057199

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.