Evidence map›Paper›PMID 38686215›Full record

Articlenpj antimicrobials and resistance2023

Functionally distinct mutations within AcrB underpin antibiotic resistance in different lifestyles.

Eleftheria Trampari, Filippo Prischi, Attilio V Vargiu, Justin Abi-Assaf, Vassiliy N Bavro, Mark A Webber

Abstract read
In one paragraph

Article in npj antimicrobials and resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Azithromycin-resistantJAC-antimicrobial resistance · 2026
    Article
  2. Envelope destabilization by AcrABCommunications biology · 2026
    Article
  3. Frontiers in bioinformatics · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. The Evolution of Heteroresistance via Small Colony Variants inbioRxiv : the preprint server for biology · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Di-berberine conjugates as chemical probes ofbioRxiv : the preprint server for biology · 2023
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eleftheria TrampariQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ UK.ORCID 0000-0001-8886-8442
Filippo PrischiSchool of Life Sciences, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ UK.
Attilio V VargiuDepartment of Physics, University of Cagliari, S. P. 8, km. 0.700, 09042 Monserrato, Italy.
Justin Abi-AssafQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ UK.ORCID 0000-0002-3343-1865
Vassiliy N BavroSchool of Life Sciences, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ UK.ORCID 0000-0003-2330-8924
Mark A WebberQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ UK.ORCID 0000-0001-9169-7592

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance is a pressing healthcare challenge and is mediated by various mechanisms, including the active export of drugs via multidrug efflux systems, which prevent drug accumulation within the cell. Here, we studied how

Indexed as

Antimicrobial resistanceExperimental evolution

Identifiers

PMID38686215
PMCPMC11057200

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.