Evidence map›Paper›PMID 38686210›Full record

ArticleFrontiers in endocrinology2024

Intraoperative radiofrequency ablation for unresectable abdominal paraganglioma: a case report.

Isabelle P A Magalhaes, Bibiana D Boger, Nathalia L Gomes, Guilherme L P Martins, Leomarques A Bomfim, Gustavo F C Fagundes, Roberta S Rocha, Fernando M A Coelho, Jose L Chambo, Ana Claudia Latronico and 5 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Isabelle P A MagalhaesAdrenal Unit, Laboratory of Molecular and Cellular Endocrinology, LIM/25, Division of Endocrinology and Metabolism, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Bibiana D BogerAdrenal Unit, Laboratory of Molecular and Cellular Endocrinology, LIM/25, Division of Endocrinology and Metabolism, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Nathalia L GomesDivision of Endocrinology, Santa Casa de Belo Horizonte, Belo Horizonte, Brazil.
Guilherme L P MartinsInterventional Radiology, Cancer Institute of São Paulo State (ICESP), University of Sao Paulo Medical School, Sao Paulo, Brazil.
Leomarques A BomfimRadiology Institute InRad, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Gustavo F C FagundesAdrenal Unit, Laboratory of Molecular and Cellular Endocrinology, LIM/25, Division of Endocrinology and Metabolism, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Roberta S RochaDivision of Endocrinology, Santa Casa de Belo Horizonte, Belo Horizonte, Brazil.
Fernando M A CoelhoRadiology Institute InRad, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Jose L ChamboDivision of Urology, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Ana Claudia LatronicoAdrenal Unit, Laboratory of Molecular and Cellular Endocrinology, LIM/25, Division of Endocrinology and Metabolism, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Maria Candida B V FragosoAdrenal Unit, Laboratory of Hormones and Molecular Genetics LIM/42, Division of Endocrinology and Metabolism, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Ana O HoffDivision of Endocrine Oncology, Cancer Institute of São Paulo State (ICESP), University of Sao Paulo Medical School, Sao Paulo, Brazil.
Berenice B MendoncaAdrenal Unit, Laboratory of Hormones and Molecular Genetics LIM/42, Division of Endocrinology and Metabolism, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Marcos R MenezesInterventional Radiology, Cancer Institute of São Paulo State (ICESP), University of Sao Paulo Medical School, Sao Paulo, Brazil.
Madson Q AlmeidaAdrenal Unit, Laboratory of Molecular and Cellular Endocrinology, LIM/25, Division of Endocrinology and Metabolism, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For pheochromocytoma and paraganglioma (PPGL), the efficacy of percutaneous ablative therapies in achieving control of metastatic tumors measuring <3 cm had been demonstrated in only few reports, and intraoperative radiofrequency ablation (RFA) of locally invasive primary PPGLs has not been reported. We presented the case of a 31-year-old man who had a 9-cm functioning unresectable PPGL. He was treated with 13 cycles of cytotoxic chemotherapy without objective tumor response, according to the Response Evaluation Criteria in Solid Tumors (RECIST). Subsequently, magnetic resonance imaging revealed a 9.0 × 8.6 × 6.0-cm retroperitoneal mass that extended to the inferior portion of the inferior vena cava, the inferior mesenteric artery, and the infrarenal aorta. Biochemical evaluation demonstrated high level of plasma normetanephrine (20.2 nmol/L, normal range <0.9 nmol/L). Genetic investigation showed the germline pathogenic variant c.1591delC (p. Ser198Alafs*22) in the

Indexed as

ParagangliomaRadiofrequency AblationAbdominal NeoplasmsAdultHumansMaleRetroperitoneal Neoplasmsablationintraoperativeparagangliomaradiofrequencyunresectable

Identifiers

PMID38686210
PMCPMC11056501

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.