Evidence map›Paper›PMID 38686051›Full record

ArticleOncology research2024

miR-200b-3p accelerates progression of pituitary adenomas by negatively regulating expression of RECK.

Xiaoxi Wang, Yanfei Jia, Qiang Li, Qiang Yang, Yingfeng Liu, Beifeng Wei, Xiang Niu, Yinjie Zhang, Xiaodong Luo, Ziyu Zhao and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaoxi WangDepartment of Neurosurgery, Tianshui First People's Hospital, Tianshui, China.
Yanfei JiaDepartment of Neurosurgery, The Second Affiliated Hospital of Lanzhou University, Lanzhou, China.
Qiang LiDepartment of Neurosurgery, The Second Affiliated Hospital of Lanzhou University, Lanzhou, China.
Qiang YangDepartment of Neurosurgery, The Second Affiliated Hospital of Lanzhou University, Lanzhou, China.
Yingfeng LiuDepartment of Neurosurgery, Tianshui First People's Hospital, Tianshui, China.
Beifeng WeiDepartment of Neurosurgery, Tianshui First People's Hospital, Tianshui, China.
Xiang NiuDepartment of Neurosurgery, Tianshui First People's Hospital, Tianshui, China.
Yinjie ZhangDepartment of Neurosurgery, Tianshui First People's Hospital, Tianshui, China.
Xiaodong LuoDepartment of Neurosurgery, The Second Affiliated Hospital of Lanzhou University, Lanzhou, China.
Ziyu ZhaoDepartment of Neurosurgery, Tianshui First People's Hospital, Tianshui, China.
Peng WangDepartment of Neurosurgery, Tianshui First People's Hospital, Tianshui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNA (miR)-200b-3p has been associated with many tumors, but its involvement in pituitary adenoma is unclear. This study investigated the molecular mechanism underlying miR-200b-3p regulation in pituitary adenomas to provide a theoretical basis for treatment. Bioinformatics was used to analyze pituitary adenoma-related genes and screen new targets related to RECK and miRNA. As well, the relationship between miR-200b-3p and RECK protein was verified using a double-luciferase reporter gene assay. The expression of miR-200b-3p in clinical samples was analyzed by

Indexed as

AdenomaApoptosisGene Expression Regulation, NeoplasticGPI-Linked ProteinsMicroRNAsPituitary NeoplasmsAnimalsCell Line, TumorCell MovementCell ProliferationDisease ProgressionFemaleHumansMaleRatsTumor Suppressor ProteinsGPI-Linked ProteinsMicroRNAsMIRN200 microRNA, humanMIRN200 microRNA, ratRECK protein, humanReck protein, ratTumor Suppressor ProteinsMatrix metalloproteinasemiR-200b-3pPituitary adenomasRECK

Identifiers

PMID38686051
PMCPMC11055999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.