Evidence map›Paper›PMID 38686038›Full record

ArticleJBMR plus2024

Osteoporosis GWAS-implicated

Gurcharan Kaur, James A Pippin, Solomon Chang, Justin Redmond, Alessandra Chesi, Andrew D Wells, Tristan Maerz, Struan F A Grant, Rhima M Coleman, Kurt D Hankenson and 1 more

Abstract read
In one paragraph

Article in JBMR plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gurcharan KaurDepartment of Biomedical Engineering, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
James A PippinCenter for Spatial and Functional Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Solomon ChangDepartment of Orthopaedic Surgery, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Justin RedmondDepartment of Biomedical Engineering, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Alessandra ChesiCenter for Spatial and Functional Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Andrew D WellsCenter for Spatial and Functional Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Tristan MaerzDepartment of Orthopaedic Surgery, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Struan F A GrantCenter for Spatial and Functional Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Rhima M ColemanDepartment of Biomedical Engineering, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Kurt D HankensonDepartment of Biomedical Engineering, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Yadav WagleyDepartment of Orthopaedic Surgery, University of Michigan Medical School, Ann Arbor, MI 48109, United States.ORCID https://orcid.org/0000-0002-1261-4267

Funding

TR&D-4: Growing Tissue in the Scalable, Modular, Automated, and Closed (SMAC) FoundryP41EB021911 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI JEAN F WELTER · 2016 to 2026
$13.9M
Preparation and Distribution of Adult Stem CellsP40OD011050 · OD · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI PROCKOP, DARWIN JOHNSON · 2012 to 2017
$6.0M
Discovery of osteoblast and osteoclast bone mass effector genes using advanced genomicsR01AG072705 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Struan F A Grant, Kurt David Hankenson · 2022 to 2026
$3.3M
NIA NIH HHS R01 AG072705NIBIB NIH HHS P41 EB021911NIH HHS P40 OD011050
6 · The paper itself

Abstract

Genome wide association study (GWAS)-implicated bone mineral density (BMD) signals have been shown to localize in cis-regulatory regions of distal effector genes using 3D genomic methods. Detailed characterization of such genes can reveal novel causal genes for BMD determination. Here, we elected to characterize the "

Indexed as

bone morphogenetic proteinchondrocytesDNM3OShuman mesenchymal stem cellsmiR-199a-5posteoblasts

Identifiers

PMID38686038
PMCPMC11056323

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.