ArticleFrontiers in plant science2024
Cold stress induces rapid gene-specific changes in the levels of H3K4me3 and H3K27me3 in
Article in Frontiers in plant science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Epigenetic Control of Cold Stress Tolerance in Plants: Emerging Mechanisms and Applications for Crop Improvement.International journal of molecular sciences · 2026Review
- Bivalent chromatin states and epigenetic priming in cotton: the role of H3K4me3 and H3K27me3 in cold stress memory and resilience.Epigenetics & chromatin · 2026Review
- Regulatory insights underlying apple to cold stress.Horticulture research · 2026Article
- Research Progress on Histone Modification Regulation Mechanisms and Breeding Applications in Plant Abiotic Stress Responses.Plants (Basel, Switzerland) · 2026Review
- PWO proteins are associated with PRC2 since their emergence in vascular plants.The New phytologist · 2026Article
- Epigenetic memory and systemic priming: an emerging framework for cold-resilient crops.Plant cell reports · 2026Review
- Harnessing Antioxidants for Abiotic Stress Management: Mechanistic Insights and Prospects for Sustainable Agriculture.Antioxidants (Basel, Switzerland) · 2026Review
- Integrative cross-platform transcriptomic analysis coupled with machine learning identifies candidate biomarkers of abiotic stress resilience in Arabidopsis thaliana.BMC plant biology · 2026Article
- Long Non-Coding RNAs in the Cold-Stress Response of Horticultural Plants: Molecular Mechanisms and Potential Applications.International journal of molecular sciences · 2025Review
- Cis- and trans-action of the cold-induced lncRNAs, SVALKA and SVALNA, regulate CBF1 and CBF3 in Arabidopsis.EMBO reports · 2025Article
- Genome-wide analysis of the CBF gene family and their transcriptional response to cold stress in Hibiscus mutabilis.Scientific reports · 2025Article
- Molecular and Physiological Responses of Plants that Enhance Cold Tolerance.International journal of molecular sciences · 2025Review
- Engineering cold resilience: implementing gene editing tools for plant cold stress tolerance.Planta · 2024Review
- Cold stress induces rapid gene-specific changes in the levels of H3K4me3 and H3K27me3 inFrontiers in plant science · 2024Article
- The Role of Histone Modifications in Plant Priming and Their Analysis by Chromatin Immunoprecipitation.Physiologia plantarumReview
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
When exposed to low temperatures, plants undergo a drastic reprogramming of their transcriptome in order to adapt to their new environmental conditions, which primes them for potential freezing temperatures. While the involvement of transcription factors in this process, termed cold acclimation, has been deeply investigated, the potential contribution of chromatin regulation remains largely unclear. A large proportion of cold-inducible genes carries the repressive mark histone 3 lysine 27 trimethylation (H3K27me3), which has been hypothesized as maintaining them in a silenced state in the absence of stress, but which would need to be removed or counteracted upon stress perception. However, the fate of H3K27me3 during cold exposure has not been studied genome-wide. In this study, we offer an epigenome profiling of H3K27me3 and its antagonistic active mark H3K4me3 during short-term cold exposure. Both chromatin marks undergo rapid redistribution upon cold exposure, however, the gene sets undergoing H3K4me3 or H3K27me3 differential methylation are distinct, refuting the simplistic idea that gene activation relies on a switch from an H3K27me3 repressed chromatin to an active form enriched in H3K4me3. Coupling the ChIP-seq experiments with transcriptome profiling reveals that differential histone methylation only weakly correlates with changes in expression. Interestingly, only a subset of cold-regulated genes lose H3K27me3 during their induction, indicating that H3K27me3 is not an obstacle to transcriptional activation. In the H3K27me3 methyltransferase
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