ArticleBMC endocrine disorders2024
The associations of oxidative stress and inflammatory markers with obesity in Iranian population: MASHAD cohort study.
Article in BMC endocrine disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Occupational Organophosphorus Pesticide Exposure and Metabolic Syndrome: Implications of PPARγ.Toxics · 2026Article
- Effect of vitamin D receptor gene TaqI polymorphism on vitamin D levels and biochemical, inflammatory, and oxidative stress markers in individuals with obesity.Molecular biology reports · 2026Article
- Precision nutrition in weight loss and neuroendocrine control of people with obesity: The study protocol of a factorial randomised controlled trial (GenON Programme).Diabetes, obesity & metabolism · 2026Article
- Integrating Preoperative NLR and PLR with Perioperative Clinical Factors: A Nomogram for Predicting Postoperative CRP Elevation After Laparoscopic Hysterectomy.International journal of women's health · 2026Article
- The Effect of Phototherapy on Systemic Inflammation Measured with Serum Vitamin D-Binding Protein and hsCRP in Patients with Inflammatory Skin Disease.International journal of molecular sciences · 2024Article
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11 authors.
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Abstract
backgroundLow-grade inflammation and stress oxidative condition play a role in the pathogenesis of obesity, and the serum levels of these markers, such as pro-oxidant-antioxidant balance (PAB), high-sensitivity C-reactive protein (hs-CRP), and uric acid may indicate obesity progression. In this study, we aimed to investigate the relationship between obesity with PAB, hs-CRP, and uric acid in the Iranian population.
methodsThis study was derived from the Mashhad Stroke and Heart Atherosclerotic Disorder (MASHAD) study. A total of 7985 subjects aged 35 to 65 years were divided into three groups according to body mass index (BMI) as: normal, overweight and obese groups. Anthropometric indices and biochemical parameters such as PAB, superoxide dismutase type 1 (SOD
resultsThere was a positive significant correlation between BMI and serum PAB, hs-CRP and uric acid (p < 0.001). While no statistically significant relation was observed between BMI and SOD
conclusionsGenerally, we showed a significant association between BMI and serum PAB, hs-CRP values and uric acid levels, suggesting the role of these factors as risk stratification factors for obesity.
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